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Applications of Nanotechnology in Drug Discovery and Delivery, in the Drug Discovery Update series, presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials.
This book brings together a global team of experts, making it an essential resource for researchers, drug developers, medicinal chemists, toxicologists and analytical chemists.
List of contents
Part 1: Fundamentals of Nanotechnology Application in Drug Discovery
1. Nanotechnology: History, Trends and Modern Application
2. Nanomaterials as Drug Candidates: Types, Synthesis and Preparatory Methods
3. Factors Affecting the Choice for Nanoparticles in Drug Discovery
4. Nanoparticle Formulation: Types, Steps and Procedures
5. Nanocarriers: Types, Synthesis and Fabrication Methods
6. Factors Affecting the Choice for Nanocarriers for Efficient Drug Delivery Applications
7. Characterization of Nanoparticles: Methods and Techniques
Part II: Application of Nanotechnology in Drug Discovery and Therapy
8. Applications of Nanotechnology in Pharmaceutical Products
9. Applications of Nanotechnology in Target Identification and Validation
10. Applications of Nanotechnology in Lead Identification and Optimization
11. Application of Nanotechnology in Pharmaceutical Product Delivery
12. Application of Nanotechnology in Medicine in the Treatment of Diseases
Part III: Safety Issues and Challenges
13. Nanotoxicology: Toxicity of Nanoparticles in Biomedical Application
14. In vitro and In vivo Toxicity of Metal Nanoparticles and their Drug Delivery Applications
15. Application of Nanoelectromechanical Systems for the Detection of Toxic Chemical Agents in Pharmaceutical Products: Nanobiosensor Application
16. Policy Issues, Risk Assessment and Regulations of the Application of Nanotechnology in Drug Discovery
