Oral Delivery of Therapeutic Peptides and Proteins

Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport.
Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.

List of contents

1. Formulation technologies being adopted for oral delivery of proteins and peptides
2. Modification of actives to make them more suited for oral delivery
3. Animal models and their shortcomings in assessing oral bioavailability
4. In vitro models to simulate drug absorption and transport
5. Futuristic technologies to improve oral bioavailability

Product details

• Assisted by: Anand Subramony (Editor), Puneet Tyagi (Editor)
• Publisher: Elsevier Science & Technology
• Languages: English
• Product format: Paperback / Softback
• Released: 22.08.2022
• EAN: 9780128210611
• ISBN: 978-0-12-821061-1
• Dimensions: 152 mm x 15 mm x 229 mm
• Weight: 500 g
• Illustrations: 40 illustrations (15 in full color)
• Subjects: Natural sciences, medicine, IT, technology > Biology > Biochemistry, biophysics; Social sciences, law, business > Business > Individual industrial sectors, branches; SCIENCE / Life Sciences / Biochemistry, MEDICAL / Pharmacology, SCIENCE / Life Sciences / Biophysics, biochemistry, Pharmacology, Biophysics, Manufacturing industries, Pharmaceutical industries