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Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990's, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis.
HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer's disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource.
List of contents
1. MRI Acquisition Techniques
2. The Physics of Hyperpolarized Gas MRI
3. Dynamic Imaging of Lung Ventilation and Gas Flow With Hyperpolarized Gas MRI
4. Persistence of Ventilation Defects in Asthmatics
5. Hyperpolarized 3He Gas MRI Studies of Pulmonary Disease
6. Pediatric Imaging and Cystic Fibrosis
7. Hyperpolarized Gas MRI of Radiation-Induced Lung Injury
8. Development and Application of Mouse Imaging Using Hyperpolarized Xenon
9. Quantitative Ventilation Imaging Using Hyperpolarized Gas and Multibreath Imaging Sequences
10. PAO2 Mapping Using HP Gas MRI
11. Hyperpolarized Xenon-129 Dissolved-Phase Magnetic Resonance Imaging
12. Lung Morphometry With HP Gas Diffusion MRI: From Theoretical Models to Experimental Measurements
13. CT and MRI Gas Ventilation Imaging of the Lungs
14. Hyperpolarized Gas MRI of the Lung in Asthma
15. Oxygen-Enhanced MR Imaging for Lung: Basics and Clinical Applications
16. Brain Imaging Using Hyperpolarized Xenon MRI
17. Xenon Biosensor HyperCEST MRI
18. Pulmonary Imaging Using 19F MRI of Inert Fluorinated Gases
19. Surface Quadrupolar Relaxation (SQUARE) Contrast in Pulmonary MRI With Hyperpolarized 83Kr
20. Overview & Future Directions