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Klotho is the latest edition of a series first published in 1943 on Vitamins and Hormones and the longest-running serial published by Academic Press. It provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic, with volumes focusing on a single molecule or on a disease that is related to vitamins or hormones that are interpreted broadly so that related substances, such as transmitters, cytokines, growth factors, and others can be reviewed.
List of contents
1. Klotho-Related Protein KLrP: Structure and FunctionsYasuhiro Hayashi and Makoto Ito2. The FGF21 Receptor Signaling Complex: KLOTHO?, FGFR1c and Other Regulatory InteractionsDawn M. Kilkenny and Jonathan V. Rocheleau3. Klotho-Dependent Cellular Transport RegulationMentor Sopjani and Miribane Dërmaku-Sopjani4. Klotho and the Growth Hormone/Insulin-like Growth Factor 1 Axis: Novel Insights Into Complex InteractionsTami Rubinek and Dalit Modan-Moses 5. Klotho Prevents Translocation of NF?BPaula Buendía, Rafael Ramírez, Pedro Aljama and Julia Carracedo6. The FGF23/KLOTHO Regulatory Network and its Roles in Human DisordersSaori Kinoshita and Masanobu Kawai7. MicroRNA-34a and Impaired FGF19/21 Signaling in ObesityTing Fu and Jongsook Kim Kemper8. The Role of Alpha-Klotho as a Universal Tumor SuppressorTami Rubinek and Ido Wolf9. Klotho is a Neuroprotective and Cognition-Enhancing ProteinCarmela R. Abraham, Patrick C. Mullen, Tracey Tucker Zhou, Cidi Chen and Ella Zeldich10. Function and Change with Aging of ?-Klotho in the KidneyKeiko Akasaka-Manya, Hiroshi Manya and Tamao Endo11. ?Klotho and Chronic Kidney DiseaseJavier A. Neyra and Ming Chang Hu12. Deficiency of Soluble ?-Klotho as an Independent Cause of Uremic CardiomyopathyJian Xie, Yueh-Lin Wu and Chou-Long Huang
