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This book covers mechanobiology, growth, remodeling, and clinical implications of coronary artery disease treatment. This volume presents a comprehensive overview of coronary circulation, including growth and remodeling of coronary vasculature, implications to cardiology, and implications to cardiovascular surgery. General principles of biomechanical homeostasis and mechanobiology are outlined. Specifics topics covered include endothelial mechano-transduction, flow reversal, uniform shear, stress & strain hypotheses, scaling laws in coronary artery disease, growth, and aging, and coronary retroperfusion.
Coronary Circulation: Mechanobiology, Growth, Remodeling and Clinical Implications is a vital resource for coronary physiologists and cardiovascular disease researchers and bioengineers who want to learn more about mechanobiology and clinical implications to coronary circulation in health and disease.
List of contents
Biomechanical Homeostasis.- Mechano-Biology.- Growth and Remodeling of Coronary Vasculature.- Growth and Remodeling: Coronary Veins and Therapeutic Implications.- Growth and Remodeling: Network Flow Analysis.- Scaling Laws of Growth and Remodeling.- Design Rules for Treatment of Coronary Bifurcation Lesions.- Computational Fluid Dynamics of Coronary Artery Disease.- Hemodynamic Design of Coronary Graft.
About the author
Dr. Ghassan S Kassab is Chair at California Medical Innovations Institute.
