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The latest edition of the seminal reference on the care and management of laboratory and research animals
The newly revised ninth edition of The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals delivers an up-to-date and authoritative exploration on worldwide developments, current thinking, and best practices in the field of laboratory animal welfare science and technology.
The gold standard in laboratory and captive animal care and management references, this latest edition continues the series' tradition of excellence by including brand-new chapters on ethical review, the care of aged animals, and fresh guidance on the care of mole rats, corvids, zebrafish, and decapods.
The book offers introductory chapters covering a variety of areas of laboratory animal use, as well as chapters on the management and care of over 30 different taxa of animals commonly utilised in scientific procedures and research around the world. It also provides:
* A thorough introduction to the design of animal experiments, laboratory animal genetics, and the phenotyping of genetically modified mice
* Comprehensive explorations of animal welfare assessment and the ethical review process
* Practical discussions of legislation and oversight of the conduct of research using animals from a global perspective
* In-depth examinations of the planning, design, and construction of efficient animal facilities, special housing arrangements, and nutrition, feeding, and animal welfare
The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals Ninth Edition is essential for laboratory animal scientists, veterinarians, animal care staff, animal care regulatory authorities, legislators, and professionals working in animal welfare non-governmental organizations.
List of contents
List of contributors vii
Foreword xi
1 Introduction 1
Claire Richardson and Huw Golledge
Part 1 Implementing the Three Rs in research using animals 3
2 The Three Rs 5
Adrian Smith and Jon Richmond
3 The design of animal experiments 23
Simon T. Bate and S. Clare Stanford
4 An introduction to laboratory animal genetics 40
Michelle Stewart and Sara Wells
5 Phenotyping of genetically modified mice 54
Jan-Bas Prins and Sara Wells
6 Brief introduction to welfare assessment: a 'toolbox' of techniques 64
Jennifer Lofgren
7 Welfare and 'best practice' in field studies of wildlife 84
Julie Lane and Robbie A. McDonald
8 Legislation and oversight of the conduct of research using animals: a global overview 101
Kathryn Bayne, Javier Guillen, Malcolm P. France and Timothy H. Morris
9 Planning, design and construction of the modern animal facility 122
Ken Applebee, Christopher Sear and Steven Cubitt
10 Environmental enrichment: animal welfare and scientific validity 137
Hanno Würbel and Janja Novak
11 Special housing arrangements 150
Mike Dennis
12 Transportation of laboratory animals 171
Sonja T. Chou, Donna Clemons, Nicolas Dudoignon, Guy Mulder and Aleksandar Popovic
13 Nutrition, feeding and animal welfare 191
Graham Tobin and Annette Schuhmacher
14 Attaining competence in the care of animals used in research 220
Bryan Howard and Marcel Gyger
15 The use of positive reinforcement training techniques to enhance the care and welfare oflaboratory and research animals 236
Gail Laule
16 3Rs considerations when using ageing animals in science 251
J. Norman Flynn, Linda Horan, Carl S. Tucker, David Robb and Michael J.A. Wilkinson
17 Euthanasia and other fates for laboratory animals 268
Huw Golledge
18 Ethics review of animal research 281
I. Anna S. Olsson and Peter Sandøe
Appendix 294
Penny Hawkins and Maggy Jennings
Part 2 Species kept in the laboratory 297
Mammals 299
19 The laboratory opossum 301
John L. VandeBerg and Sarah Williams-Blangero
20 Tree Shrews 324
Eberhard Fuchs
Rodentia and Lagomorpha 340
21 The laboratory mouse: Biology, behaviour, enrichment and welfare: first principles and realsolutions for laboratory mice 340
Kathleen R. Pritchett-Corning and Joseph P. Garner
22 The laboratory rat 379
Sietse F. de Boer and Jaap M. Koolhaas
23 The laboratory gerbil 400
Elke Scheibler
24 The Syrian hamster 419
Christina Winnicker and K.R. Pritchett-Corning
25 Voles 430
Petra Kirsch
26 The naked mole-rat (Heterocephalus glaber) 442
Chris G. Faulkes
Appendix A 459
27 The guinea pig 465
Sylvia Kaiser, Christine Krüger and Norbert Sachser
28 The laboratory rabbit 484
Lena Lidfors and Therese Edström
Carnivora 506
29 The ferret 506
Maggie Lloyd
30 The laboratory dog 518
Laura Scullion Hall and Jackie Boxall
31 The domestic cat 546
Emma Desforges
Ungulates 570
32 Pigs and minipigs 570
Adrian Zeltner and Henrik Duelund Pedersen
33 Cattle 596
Ute Weyer and Shellene Hurley
34 Sheep and goats 609
Colin L. Gilbert and Cathy M. Dwyer
35 The Horse 628
Heather Ewence and Fleur Whitlock
Non-Human Primates 662
36 The mouse lemurs 662
Jennifer Wittkowski, Annette Klein, Annika Kollikowski, Marina Scheumann, Daniel Schmidtke, Elke Zimmermann and Ute Radespiel
37 Marmosets and tamarins 683
Hannah M. Buchanan-Smith
38 Capuchin monkeys 707<
About the author
Huw Golledge is Chief Executive Officer and Scientific Director at the Universities Federation for Animal Welfare (UFAW), UK. He has served as a member of the UK Animals in Science Committee which advises the government on the use of animals in research.
Claire Richardson has over twenty years of experience in the field of laboratory animal welfare and has worked as a laboratory animal veterinarian as well as an animal welfare scientist. She is a member of the editorial team at the Universities Federation for Animal Welfare (UFAW), UK.
