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In this issue of
Clinics in Perinatology, guest editor Dr. Lina Chalak brings her considerable expertise to the topic of
Perinatal Asphyxia: Moving the Needle. According to the World Health Organization, birth asphyxia accounts for an estimated 900,000 deaths each year and is one of the primary causes of early neonatal mortality. In this issue, top experts provide current clinical information needed to improve outcomes in newborns, while looking at results from clinical trials, neuroimaging biomarkers, and low-resource settings.
- Contains 15 relevant, practice-oriented topics including the role of a maternal-placental-fetal triad; treating seizures and improving newborn outcomes; advances in neuroimaging biomarkers and scoring; moving the needle in low-resource settings: is hypothermia a friend or a foe?; ethical and medicolegal perspectives on cooling: where to draw the line?; and more.
- Provides in-depth clinical reviews on perinatal asphyxia, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
List of contents
Causes and Terminology in Neonatal Encephalopathy: What is in a Name? Neonatal Encephalopathy, Hypoxic-ischemic Encephalopathy or Perinatal Asphyxia
Neonatal Encephalopathy is a Complex Phenotype Representing Reproductive and Pregnancy Exposome Effects on the Maternal-Placental-Fetal Triad
Uncovering the Role of Inflammation with Asphyxia in the Newborn
Reverse Therapy: Impact of Hyperthermia and Rewarming on Newborn Outcomes
Treating Seizures and Improving Newborn Outcomes for Infants with Hypoxic[1]Ischemic Encephalopathy
Hypothermia for Hypoxic-ischemic Encephalopathy: Second-generation Trials to Address Gaps in Knowledge
A New Horizon for Understanding the Comparative Effectiveness for Cooling Prospectively Infants with Mild Encephalopathy
Key Inflammatory Biomarkers in Perinatal Asphyxia: A Comprehensive Review
Advances in Neuroimaging Biomarkers and Scoring
Advances in Electroencephalographic Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy
Moving the Needle in Low-Resource Settings: Is Hypothermia a Friend or a Foe?
Long-Term Outcomes Following Hypoxic Ischemic Encephalopathy
Communicating with Parents About Therapeutic Hypothermia and Hypoxic Ischemic Encephalopathy: Integrating a Palliative Care Approach into Practice
Ethical and Legal Perspectives on the Treatment of Hypoxic Ischemic Encephalopathy in the Newborn
Pipeline to Neonatal Clinical Transformation: The Importance of Preclinical Data
