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Genetics and Epigenetics of Genitourinary Diseases aims to provide a comprehensive collection of data on genetics and epigenetics in almost all genitourinary diseases for researchers, clinicians, and graduate students. This book discusses several genetic and epigenetic changes like DNA methylation, mutations, single nucleotide polymorphisms, DNA rearrangements, chromosomal remodeling, microsatellite instability, and chromosomal instability (CIN) in genitourinary cancers. This book is split into 18 chapters, beginning with the importance of genetics and epigenetics in genitourinary diseases. It then goes on to cover the genetics and epigenetics of various diseases and tumors. Certain chapters present novel techniques of next-generation sequencing (NGS). Furthermore, RNA-Seq is discussed as a sequencing technique that uses NGS to reveal the presence and quantity of RNA in a biological sample. This book is a valuable resource for researchers, practitioners, and students in genetics and epigenetics who want to broaden their understanding of the field.
List of contents
1. Introduction: Importance of genetic and epigenetics in genitourinary diseases 2. Genetic change definition 3. Epigenetic modifications definition 4. Genetic and epigenetics of kidney disease 5. Genetic and epigenetics of bladder disease 6. Genetic and epigenetics of prostate disease 7. Genetic and epigenetics of testis disease 8. Genetic and epigenetics of Ureteral disease 9. Genetic and epigenetic Urolithiasis 10. Infertility and the chromosomal abnormalities 11. Biology of cancer 12. Genetic and epigenetics of testis tumor 13. Genetic and epigenetics of Kidney tumor 14. Genetic and epigenetics of prostate tumor 15. Genetic and epigenetics of bladder tumor
About the author
Dr Seyed Mohammad Kazem Aghamir is a full professor at Tehran University of Medical Sciences and runs the urology research center. He conducts several projects at URC in the field of basic science and high technology in urological malignancies. Very recently, he has published two books “Liquid Biopsy in Urogenital Cancers and its Clinical Utility” and “stem cell in urology”.
