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This book brings together the exciting new findings that will bring us closer to a better understanding of the alterations of neuronal connectivity in autistic brains. This volume authoritatively covers the epidemiology, physiology, neurodevelopment, genetics, environmental influences, imaging studies, neuroanatomy, and neurochemistry of autism spectrum disorders. While the neurobiology of autism is still a long way from being understood, this book posits techniques, such as using brain imaging to find signatures in early days of life, that could help move the diagnosis and help identify neural pathways. Understanding these mechanisms opens the possibility to pharmacological, behavioral, and psychosocial therapeutic interventions. With contributions from the leading international autism researchers, Neurobiology of Autism Spectrum Disorders is the go-to reference for researchers and clinicians with an interest in understanding the underlying neurobiologyof autism spectrum disorders.
List of contents
Dysfunctional circuit mechanisms of sensory processing in FXS and ASD: insights from mouse models.- Theory of Mind in Autism.- Prenatal and Early Life Environmental Stressors: Chemical Moieties Responsible for The Development of Autism Spectrum Disorder.- Animal models of ASD.- Mitochondrial dysfunction in autism spectrum disorders.- The usability of mouse models to study the neural circuity in autism spectrum disorder: regulatory mechanisms of core behavioral symptoms.- Seizures in Mouse Models of Autism.- Lipid-Related Pathophysiology of ASD.- Perinatal Insulin-like Growth Factor as a Risk Factor for Autism.- Prophylactic Treatment of ASD Based on Sleep-Wake Circadian Rhythm Formation in Infancy to Early Childhood?.- Imbalances of inhibitory and excitatory systems in autism spectrum disorders.- lead and autism.- Epidemiological surveys of ASD: current findings and new directions.- Metabolic Approaches to the treatment of Autism Spectrum Disorders.- Autism and Neurodiversity.- Principal findings of auditory evoked potentials in autism spectrum disorder.- Genes and their involvement in the pathogenesis of autism spectrum disorder: Insights from earlier genetic studies.- Electrophysiology of semantic processing in ASD.- Gestational exposure to Di-n-butyl phthalate induces autism-like behavior through inhibition of neuro-steroidogenesis.
About the author
Abdeslem El Idrissi, PhD, is Professor of Neuroscience and a former Chair of the Biology Department at the College of Staten Island, City University of New York. He is also a Director of the Medical Technology Program and holds an appointment at the Graduate Center of the CUNY in the Neuroscience subprogram where he served as chairman. Dr. El idrissi’s research interest focuses on the developmental maturation of the GABAergic system and the developmental disabilities associated with the abnormal development of this system. He is the editor of the Springer book, Taurine 8 and 11.
Dan McCloskey, PhD, is Associate Professor and Chairperson, Department of Psychology at the College of Staten Island, City University of New York. His research is focused on understanding the brain systems involved in everyday social behavior.
Summary
This book brings together the exciting new findings that will bring us closer to a better understanding of the alterations of neuronal connectivity in autistic brains. This volume authoritatively covers the epidemiology, physiology, neurodevelopment, genetics, environmental influences, imaging studies, neuroanatomy, and neurochemistry of autism spectrum disorders. While the neurobiology of autism is still a long way from being understood, this book posits techniques, such as using brain imaging to find signatures in early days of life, that could help move the diagnosis and help identify neural pathways. Understanding these mechanisms opens the possibility to pharmacological, behavioral, and psychosocial therapeutic interventions. With contributions from the leading international autism researchers, Neurobiology of Autism Spectrum Disorders is the go-to reference for researchers and clinicians with an interest in understanding the underlying neurobiologyof autism spectrum disorders.
