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Anandamide in Health and Disease, a volume in the
Molecular Mediators in Health and Disease: How Cells Communicate series, is a complete reference on the roles of anandamide in health and disease states. Following the characteristics of the series, this book provides a comprehensive overview of the effects of the mediator on human health.
The book is divided into two parts, the first of which provides background information on biology, regulation, synthesis and degradation and modulation of anandamide. The second part is dedicated to covering the role of anandamide in various diseases. A comprehensive panel of authors cover several somatic and psychiatric disorders, such as anxiety disorders, mood disorders, psychosis and substance use disorders. Additionally, the role of anandamide across epilepsy, Alzheimer's disease, and digestive conditions is explored.
Anandamide in Health and Disease is the perfect reference for bioscience researchers seeking to understand anandamide pharmacology, biochemistry, cellular, and molecular biology. Clinicians may also be interested in better understanding the wide-ranging health effects of the mediator.
List of contents
PART I Introduction to anandamide1 Regulation of the levels of anandamide and its bioactive congeners by biosynthesis and degradation
Vincenzo Di Marzo and Cristoforo Silvestri2 Imaging the endocannabinoid enzyme fatty acid amide hydrolase in the living human brain
Claire Shyu, Shamantha Lora, Laura M. Best, Sheldon Bereznick and Isabelle Boileau3 Anandamide: From modulation of neuronal excitation to antimicrobial activities--What is in common?
Ronit Vogt Sionov and Doron SteinbergPART II Anandamide in diseases4 Anandamide and mood disorders
Jacklynn M. Fitzgerald and Cecilia J. Hillard5 Anandamide and anxiety
Sara Liane Kroll and Leah M. Mayo6 Anandamide and disease. Role in stress, fear, and PTSD
Luke J. Ney and Allison Matthews7 Anandamide in disease: Role in psychosis
M. Belen Blasco, Carlos A. Pretell Annan and Romina Mizrahi8 Anandamide in personality disorders
Nathan J. Kolla and Michelle De Pol9 A brief review of anandamide in cannabis use and cannabis use disorder
Raesham Mahmood, Claudia Poluga, Isabelle Boileau and Laura M. Best10 Anandamide signaling dysfunction in the development of alcohol use disorders
Balapal S. Basavarajappa11 Role of Anandamide in Nicotine Addiction
Bernard Le Foll12 The role of anandamide in the sleep--wake cycle
Monica Mendez D¿az, Yalitza Azucena Alvarado Ram¿rez, Aline Ostos Valverde, Oscar E. Prospero Garc¿a and Andrea M. Herrera Sol¿s13 Anandamide in disease: The good and bad in epilepsy
Renaud Gom, Pasindu Wickramarachchi, Roberto Colangeli and G. Campbell Teskey14 Role of anandamide in Alzheimer’s disease
Dina Medina-Vera and Simone Tambaro15 The role of anandamide in digestive and defensive functions of the gut
Keith A. Sharkey and Derek K.L. Tsang16 The role of anandamide and the endocannabinoids in the treatment and regulation of nausea and vomiting
Erin M. Rock and Linda A. Parker
About the author
Dr. Bernard Le Foll is a Clinician Scientist specializing in Addiction. He is Chair of Addiction Psychiatry within the Department of Psychiatry of University of Toronto. He is Head of the Translational Addiction Research Laboratory in the Campbell Family Mental Health Research Institute. He is also the Lead, Clinical Research Innovation Service within the Addiction Division at CAMH. He is Head of the Alcohol Research and Treatment Clinic at CAMH. He is Professor at University of Toronto in the departments of Family and Community Medicine, Pharmacology and Toxicology, Psychiatry ,Institute of Medical Sciences and Dalla Lana School of Public Health.
