Read more
Urinary Incontinence: Integrating Science and Clinical Practice provides a succinct elaboration of the current understanding of the system function of lower urinary tract physiology from world-leading contributors and clinical relevance. Key influences on mechanisms and therapies within urinary incontinence are presented for proper understanding of the scientific basis of incontinence and its clinical treatment. The first part of the book is dedicated to System Physiology: Function and Adaptation. In this section an anatomical sequence is followed for presenting the chapters, moving from the lower urinary tract organs upwards through the spinal centers to the brain, thus revealing what is known and unknown.
The second is dedicated to Incontinence: Mechanism and Therapy. In this clinical application section, the chapters will be derived from the clinical classification of incontinence, incorporating some of the major unanswered questions, such as; what urodynamics can tell us about the passive physical and contractile properties of the bladder; how neuromodulation works; the sensations arising from the LUT; how the physical properties of the outflow tract are obtained from urethral pressure profiles; how PET and fMRI images are interpreted and what principles of drug design and outcome measures are validated as repeatable.
List of contents
Part 1. System Physiology: Function and adaptation1. Bladder integrative physiology
2. Sensory information from the lower urinary tract
3. Conscious sensation
4. Cerebral control of storage/voiding cycle
5. Synergy of lower urinary tract function
6. Inflammation, fibrosis and collateral influences
Part 2. Incontinence: Mechanism and therapy7. Urgency urinary incontinence
8. Stress urinary incontinence
9. Situational incontinence.
10. Enuresis, voiding dysregulation and disinhibited voiding
About the author
Professor Marcus Drake is Physiological Urology at Bristol University, UKDr. Bahareh Vahabi is a Senior Lecturer in Physiology with a distinguished record of academic and research achievements. Holding a PhD in Pharmacology, Bahareh specialises in benign lower urinary tract disorders, contributing over 13 years of expertise to their field.As an experienced academic and educator, Bahareh has received recognition for her teaching excellence, including a Postgraduate Teaching Certificate with distinction and Fellowship of the Higher Education Academy. She is committed to providing students with a research-informed learning experience, with her principal contribution being leading and teaching modules in Anatomy, Physiology, Pharmacology, and Pathophysiology at both undergraduate and postgraduate levels.In addition to her teaching responsibilities, Bahareh is an experienced and well-established researcher with a proven track record of success. She has supervised over 80 undergraduate final year project students and numerous MD and PhD students, guiding them to successful completion. She has authored publications in high impact journals. Bahareh also acts as a reviewer for prestigious journals and grant awarding bodies, contributing to the advancement of scientific knowledge in lower urinary tract pharmacology and physiology. Bahareh also plays a pivotal role in fostering international collaborations and partnerships in her role as International Partnership Lead for the School of Applied Sciences. Leveraging her expertise and network, she has established successful research exchange programs and forged new academic partnerships, enhancing the School’s global presence and facilitating knowledge exchange across borders.
Mathijs de Rijk is a dedicated researcher specializing in the intersection of neuroscience and urology at Maastricht University. With a profound interest in understanding the complexities of neural mechanisms and their implications for urological health, Mathijs has contributed significantly to the field through innovative research and collaboration.
