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Klappentext Recurrent Pregnancy LossEdited byOle B Christiansen, MD, D.M.Sc., Rigshospitalet, Copenhagen and AalborgUniversityHospital, Aalborg, DenmarkRecurrent Pregnancy Loss is a silent problem for many womenThe spontaneous loss of a pregnancy in the first 22 weeks is often not recorded as the mother needed no medical or surgical treatment. Women who repeatedly suffer this tragedy can go unheard as a result. Gynecologists can feel unable to help.But they can help. Research is showing how to identify women who suffer recurrent pregnancy loss and which treatments might prevent a further recurrence. Gynecologists are learning how to monitor subsequent pregnancies for the early signals of problems.Recurrent Pregnancy Loss provides a practical approach to this hidden clinical challenge. The highly experienced, international author team explores:* How to obtain a relevant history* Which investigations to order* The physiological reasons behind recurrent pregnancy loss* The best approach to treatment* How to monitor patients in subsequent pregnanciesClinical in approach, practical in execution, with the patient at the centre, Recurrent Pregnancy Loss guides you as you support your patients. Zusammenfassung Recurrent Pregnancy LossEdited byOle B Christiansen, MD, D.M.Sc., Rigshospitalet, Copenhagen and AalborgUniversityHospital, Aalborg, DenmarkRecurrent Pregnancy Loss is a silent problem for many womenThe spontaneous loss of a pregnancy in the first 22 weeks is often not recorded as the mother needed no medical or surgical treatment. Women who repeatedly suffer this tragedy can go unheard as a result. Gynecologists can feel unable to help.But they can help. Research is showing how to identify women who suffer recurrent pregnancy loss and which treatments might prevent a further recurrence. Gynecologists are learning how to monitor subsequent pregnancies for the early signals of problems.Recurrent Pregnancy Loss provides a practical approach to this hidden clinical challenge. The highly experienced, international author team explores:* How to obtain a relevant history* Which investigations to order* The physiological reasons behind recurrent pregnancy loss* The best approach to treatment* How to monitor patients in subsequent pregnanciesClinical in approach, practical in execution, with the patient at the centre, Recurrent Pregnancy Loss guides you as you support your patients. Inhaltsverzeichnis Series Foreword viiContributors viiiPreface to the first edition xii1 Obtaining the Relevant History 1Ole B. Christiansen2 Which Investigations Are Relevant? 10Paulien G. de Jong, Emmy van den Boogaard, Claudia R. Kowalik, Rosa Vissenberg, Saskia Middeldorp and Mariëtte Goddijn3 NK Cells in Peripheral Blood and the Endometrium 29Gavin Sacks4 Cytokines and Cytokine Gene Polymorphisms in Recurrent Pregnancy Loss 38Silvia Daher, Maria Regina Torloni and Rosiane Mattar5 How to Assess the Prognosis after Recurrent Miscarriage 46Howard J.A. Carp6 Which Treatments Should be Offered? PGD/PGS, Allogeneic Lymphocyte Immunization, Intravenous Immunoglobulin 61Henriette Svarre Nielsen and Ole B. Christiansen7 Which Treatment Should be Offered? Heparin/Aspirin, Progesterone, Prednisolone 70Muhammad A. Akhtar and Siobhan Quenby8 Which Treatment Should be Offered: Metformin, hCG, GM-CSF/G-CSF, TNF-alpha Inhibitors, Standard IVF/ICSI 78Ole B. Christiansen9 Talking to Patients about Lifestyle, Behavior, and Miscarriage Risk 86Ruth Bender Atik and Barbara E. Hepworth-Jones10 E ndocrine and Ultrasonic Surveillance of Pregnancies in Patients with Recurrent Miscarriage 103Adjoa Appiah and Jemma Johns11 Obstetric Complications in Patients with Recurrent Miscarriage - How Should they be Monitoredin the Third Trimester? 115Shehnaaz Jivraj12 Recurrent Miscarriage after ART: A Double Challenge 128Elisabeth C. Larsen and Ole B. Christiansen13 How to Cope w...