Tremors

Tremor is the most common movement disorder. The breadth of work remaining in tremorpathophysiology, etiology and treatment development does not render the area intractable; on thecontrary, this is a dynamic, rich research area sure to continue its rapid growth. In Tremors, experts inthe field come together to discuss the underpinnings of neurological tremors and recent clinicalfindings in treatment models.

List of contents

• Section 1: Tremor Foundations


• Chapters


• 1. Tremor: History, background, basic definitions


• 2. Clinical classification of tremor syndromes


• 3. Neuroanatomy and physiological mechanism of tremor


• 4. Neuropathology of tremors


• 5. Neuroimaging of tremors


• 6. Genetics of tremors


• 7. Tremor in medicine and other secondary tremors


• Section 2: The Family of Tremors


• Chapters


• 8. Orthostatic tremor


• 9. Essential tremor


• 10. Voice Tremor


• 11. Tremor, dystonia, and dystonic tremor


• 12. Parkinson's disease and parkinsonian tremor


• 13. Tremor and ataxia


• 14. Myoclonus


• 15. Myorhythmia


• 16. Functional tremor


• Section 3: Tremor in the Clinic


• Chapters


• 17. Diversity and inclusivity in Parkinson's disease and essential tremor


• 18. Assessing tremor: diagnostic pearls, rating scales, and waveform recording


• 19. Treatment of tremor


• 20. Thinking and treating beyond the tremor


• 21. Tremor: Emerging and investigational treatments

About the author

Claudia Testa, MD, PhD, Professor of Neurology and Chief of the Precision Medicine and Neurogenetics Division at University of North Carolina at Chapel Hill, completed Movement Disorders Fellowship at Emory University. After joining the Emory faculty, her work shifted from bench-based systems neuroscience to multi-center collaborative clinical trial and phenotype-genotype projects. She next served as the Joan Massey Chair in Clinical Parkinson Disease at Virginia Commonwealth University, and founded the VCU Huntington Disease Program. Dr. Testas interest in tremor began with a determined patient at Emory, and the commitment of tremor patients and families continues to inspire her.

Dietrich Haubenberger, MHSc, MD is a voluntary Associate Clinical Professor in the Department of Neurosciences at the University of California, San Diego. He received his training as movement disorders neurologist at the Medical University of Vienna, Austria, after which he joined the Intramural Research Program at the National Institutes of Neurological Disorders and Stroke (NINDS), at the National Institutes of Health, where he directed a Clinical Trials Unit. His research on tremor and other movement disorders spanned across clinical-genetic studies, neurophysiology, outcome measures, and clinical trials of tremor. In 2019, Dr. Haubenberger ventured into the pharmaceutical industry, leading clinical development programs in neurological indications at Neurocrine Biosciences, Inc..

Summary

Tremor is the most common movement disorder. The breadth of work remaining in tremor pathophysiology, etiology and treatment development does not render the area intractable; on the contrary, this is a dynamic, rich research area sure to continue its rapid growth. In Tremors, experts in the field come together to discuss the underpinnings of neurological tremors and recent clinical findings in treatment models.

This volume is broken into the following sections:
· "Tremor Foundations" presents work across research modalities, providing an overview on the underpinnings of tremor as symptom and disease. Recent developments in the understanding of tremor pathology, pathophysiology, and genetics, aided by groundbreaking discoveries using neuroimaging techniques, allow glimpses into future breakthroughs to come.
·"The Family of Tremors" presents the full extended range of tremor presentations, spanning isolated tremors, tremor as one of several features of a neurological disorder, and other hyperkinetic movement phenotypes commonly referred to, mimicking or framed as tremors.
·"Tremor in the Clinic" reviews the growing knowledge range of clinical topics in tremors. Advances in assessing tremor bring pathophysiology concepts into clinical use, opening an active era in new therapeutic development. Clinical researchin tremors also now encompasses more holistic treatment approaches, novel treatment modalities, and diversity and inclusivity, all areas likely to feed back into basic etiology and pathophysiology research of this common movement disorder.

Tremors will prove to be a useful text for practicing clinicians, students and researchers focusing on movement disorders, and those living with tremor who want to learn more about their condition.

Product details

• Authors: Claudia (Founder and Director Testa M.
• Assisted by: Dietrich Haubenberger (Editor), Claudia Testa M. (Editor)
• Publisher: Oxford University Press
• Languages: English
• Product format: Hardback
• Released: 14.11.2022
• EAN: 9780197529652
• ISBN: 978-0-19-752965-2
• No. of pages: 312
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; MEDICAL / Neuroscience, MEDICAL / Neurology, Neurology & clinical neurophysiology, Neurology and clinical neurophysiology