Handbook of Bioanalysis and Drug Metabolism

List of contents

The Role of Drug Metabolism and Pharmacokinetics in Drug Discovery: Past, Present and Future. The Importance of the Physiochemical Properties of Drugs to Drug Metabolism. Sample Preparation. High Performance Liquid Chromatography in Pharmaceutical Bioanalysis. Quantitative Mass Spectronomy. Immunoassay in Bioanalysis. Phase I Metabolism. Phase II Enzymes. In vitro Techniques for Investigating Metabolism. Drug–Drug Interactions: an in vitro Approach. Clinical Impact of Drug Interactions. Preclinical Pharmacokinetics. Pharmacokinetic / Pharmacodynamic Modeling in Preclinical Drug Discovery. Toxicokinetics. Protein Binding in Plasma: A Case History of a Highly Protein Bound Drug. Metabolite Identification by Spectroscopy. Whole Body Autoradiography. Radiolabeled Studies in Man. Molecular Biology.

About the author

Gary Evans

Product details

• Authors: Gary Evans
• Assisted by: Gary Evans (Editor)
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Paperback / Softback
• Released: 25.09.2019
• EAN: 9780367394424
• ISBN: 978-0-367-39442-4
• No. of pages: 408
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; METABOLISM, MEDICAL / Pharmacology, MEDICAL / Endocrinology & Metabolism, MEDICAL / Laboratory Medicine, Pharmacology, Medical laboratory testing & techniques, Medical laboratory testing and techniques