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Unveiling the latest research in neurophysiology,
Cellular and Molecular Neurophysiology, Fifth Edition continues to stand as the only resource in the field. This book remains the standard for those who seek to explore the intricate molecular and cellular physiology of neurons and synapses.
Notably, this new edition delves even deeper into the molecular properties and functions of excitable cells, offering unparalleled insights. In this edition, there are two groundbreaking chapters. The first reviews metabotropic receptors for olfactory transduction, while the second presents cutting-edge techniques for neuroscience research. Hypothesis-driven rather than a dry presentation of facts, the content firmly based on numerous experiments performed by top experts in the field, teaches students how to build and conduct intelligent research experiments.
This book promotes a true understanding of nerve cell function and will be a useful resource for practicing neurophysiologists, neurobiologists, neurologists, and students in a graduate-level course on the topic alike.
List of contents
- Neurons
- Neuron-glial cell cooperation
- Ionic gradients, membrane potential, and ionic currents
- The voltage-gated channels of Na+ action potentials
- The voltage-gated channels of Ca2+ action potentials: generalization
- The chemical synapses
- Neurotransmitter release
- The ionotropic nicotinic acetylcholine receptors
- The ionotropic GABAA receptor
- The ionotropic glutamate receptors
- The metabotropic GABAB receptors
- The metabotropic glutamate receptors
- The metabotropic olfactory receptors
- Somatodendritic processing of postsynaptic potentials I: passive properties of dendrites
- Subliminal voltage-gated currents of the somatodendritic membrane
- Somatodendritic processing of postsynaptic potentials II. Role of subthreshold voltage-gated currents
- Somatodendritic processing of postsynaptic potentials III. Role of high-voltageeactivated currents
- Firing patterns of neurons
- Synaptic plasticity
- The adult hippocampal network
- Morphogenesis and maturation of the hippocampal network
- Chapter techniques
About the author
Constance Hammond is an INSERM director of research at the Mediterranean Institute of Neurobiology. A renowned Parkinson's disease investigator, in 2012 she became a Chevalier of the Légion d'Honneur in recognition for her services to scientific communication. Studying biology at the University of Pierre and Marie Curie and the Ecole Normale Supérieure in Paris she completed her thesis in neurosciences at the Marey Institute in Paris, directed by Prof. D. Albe-Fessard. Guided by her curiosity and her constant desire to learn, she changed lab and research domains several times. With the knowledge of other systems and the mastering of other techniques she finally came back to her first and preferred subject of research; the role of the subthalamic nucleus in the basal ganglia system in health and Parkinson's disease.
