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Zusatztext "a useful addition to the fields of both magnetic resonance (MR) as well as signal processing. ? immensely useful as a practical resource handbook to dip into from time to time and to find specific advice on issues faced during the course of work in MR techniques for cancer research. ? the best feature of this book is how it positions the very practical area of digital signal processing in the contextual framework of a much more esoteric and fundamental field-that of quantum mechanics. The direct link between quantum-mechanical spectral analysis and rational response functions and the general role of quantum mechanics in signal processing is beautifully brought out in Chapter 2. This chapter alone is worth the price of the book and will especially appeal to a multi-disciplinary audience comprising NMR spectroscopists! atomic and molecular physicists! and physicists who work in the foundations of quantum mechanics." -Kavita Dorai! Contemporary Physics ! January 2013 Informationen zum Autor Dževad Belkic is a professor of mathematical radiation physics at the Karolinska Institute in Stockholm, Sweden. Dr. Belkic’s current research activities encompass atomic collision physics, radiation physics, radiobiology, magnetic resonance physics and mathematical physics. Karen Belkic is a physician specialist in internal medicine, adjunct professor of preventive medicine at the Keck School of Medicine of the University of Southern California in Los Angeles, and senior scientist in the oncology and pathology department at the Karolinska Institute in Stockholm, Sweden. Klappentext While approaches to mathematical signal processing methods for magnetic resonance spectroscopy are known! their clinical relevance is less understood. Written by a unique interdisciplinary team! a mathematical physicist and clinical researcher! this book bridges the gap between what is known and how to apply it. The authors demonstrate the need for more advanced signal processing methods and suggest that the fast Pade transform (FPT) is optimally suited for this. They discuss how the Pade-optimization greatly improves resolution and yields maximally accurate parametric reconstructions on the metabolite concentrations which distinguish malignant from benign samples. Zusammenfassung Addressing the critical need in clinical oncology for robust and stable signal processing in MRS, this book explores cutting-edge theory-based innovations for obtaining reliable quantitative information from MR signals for cancer diagnostics. By defining the natural framework of signal processing using the well-established theory of quantum phys Inhaltsverzeichnis Basic Tasks of Signal Processing in Spectroscopy. The Role of Quantum Mechanics in Signal Processing. Harmonic Transients in Time Signals. Signal-Noise Separation via Froissart Doublets. Padé Processing for Magnetic Resonance (MR) Total Shape Spectra from in vivo Free Induction Decays (FIDs). Exact Reconstructions of Spectral Parameters by FPT. Machine Accurate Padé Quantification and Exact Signal-Noise Separation. Magnetic Resonance Spectroscopy (MRS) and Magnetic Resonance Spectroscopic Imaging (MRSI) in Neuro-Oncology: Achievements and Challenges. Padé Quantification of Malignant and Benign Ovarian MRS Data. Breast Cancer and Non-Malignant Breast Data: Quantification by FPT. Multiplet Resonances in MRS Data from Normal and Cancerous Prostate. General Discussion. Conclusions and Outlooks. ...
