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Zusatztext ?This book will help the reader to understand the kinetic modeling approach! apply it to solve real-life problems! and give the opportunity to think about future challenges. It also illustrates how to apply the principles of kinetic modeling to perform various functions. ?-ISCB News #49! June 2010 Informationen zum Autor Demin! Oleg; Goryanin! Igor Klappentext With more and more interest in how components of biological systems interact! it is important to understand the various aspects of systems biology. This book explores both the methods and applications of kinetic modeling in the field. It describe how to construct kinetic models of intracellular systems on the basis of models of individual enzymes. Zusammenfassung Focusing on one of the main pillars in the future development of systems biology, this book explores the kinetic modeling approach and how to apply it to solve real-life problems. It covers model creation techniques, model verification and validation, and simulations and interpretation of biological results. The authors describe underlying algor Inhaltsverzeichnis Introduction. Systems Biology, Biological Knowledge, and Kinetic Modelling. Cellular Networks Reconstruction and Static Modelling. Edinburgh Pathway Editor. Construction and Verification of Kinetic Models. Introduction to DBSolve. Enzyme Kinetics Modelling. Kinetic Models of Biochemical Pathways. Modelling of Mitochondrial Energy Metabolism. Application of the Kinetic Modelling Approach to Problems in Biotechnology and Biomedicine. Conclusion and Discussion. References. Index.
