Oxford Textbook of Neuromuscular Disorders

Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuromuscular Disorders covers the scientific basis, clinical diagnosis, and treatment of neuromuscular disorders with a particular focus on the most clinically relevant disorders. The book is organized into seven sections, starting with the general approach to the patient with neuromuscular disorders and then focusing on specific neuromuscular conditions affecting the peripheral nervous system from its origins at the spinal cord anterior horn on its outward course to their effector muscles and the inbound sensory pathways. Chapters on specific neuromuscular conditions are illustrated with typical case histories and their presenting features, allowing readers to put rarer conditions into their clinical context more easily. The concurrent online version allows access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint®.
This textbook will serve as a useful reference for neurologists and specialist trainees in neurology, neuroscientists, neurophysiologists, and other healthcare professionals.

List of contents

• Section 1: Approach to the patient


• 1: David Hilton-Jones and Martin R. Turner: Eliciting the history


• 2: David Hilton-Jones and Martin R. Turner: Genetic considerations


• 3: David Hilton-Jones and Martin R. Turner: Examination


• Section 2: Anterior Horn


• 4: Kevin Talbot and Martin R. Turner: Amyotrophic Lateral Sclerosis


• 5: Dirk Baumer and Kevin Talbot: Spinal muscular atrophy and hereditary motor neuropathy


• 6: Kenneth Fischbeck and Christopher Grunseich: Kennedy's disease


• 7: Robin S. Howard: Poliomyelitis


• Section 3: Peripheral Nerve: Inherited


• 8: Mary Reilly and Alex Rossor: Charcot Marie Tooth disease


• 9: Michaela Auer-Grumbach: Hereditary sensory and autonomic neuropathies


• 10: Violaine Plante-Bordeneuve: Familial amyloid polyneuropathy


• 11: Lionel Ginsberg: Inherited metabolic neuropathies


• Section 4: Peripheral Nerve: Acquired


• 12: Neil G Simon and Matthew C Kiernan: Mononeuropathies


• 13: J Gareth Llewelyn and Eleanor A Marsh: Multiple mononeuropathies


• 14: David LH Bennett and Mohamed Mahdi-Rogers: Plexopathy


• 15: Camiel Verhamme and Ivo N van Schaik: Polyneuropathies: Axonal


• 16: Pieter A van Doorn and Judith Drenthen: Polyneuropathies: Demyelinating


• 17: Stephen A Goutman, Andrea L. Smith, Stacey A. Sakowski, and Eva L. Feldman: Diabetic neuropathy


• 18: David Hilton-Jones: Peripheral nerve hyperexcitability disorders


• Section 5: Neuromuscular Junction: Inherited and Acquired


• 19: Jackie Palace and Sarah Finlayson: Inherited myasthenic syndromes


• 20: Saiju Jacob, Stuart Viegas, and David Hilton-Jones: Myasthenia gravis


• 21: Maarten J. Titulaer and Jan J G M Verschuuren: The Lambert-Eaton myasthenic syndrome


• Section 6: Muscle


• 22: Kevin M. Flanagan: The dystrophinopathies


• 23: Fiona Norwood and Kate Bushby: Limb-girdle muscular dystrophies


• 24: Emma Clement and Heinz Jungbluth: The congenital muscular dystrophies


• 25: David Hilton-Jones and Chris Turner: The myotonic dystrophies


• 26: Baziel Van Engelen, Elly van der Kooi, and Silvere van der Maarel: FSH dystrophy


• 27: Bjarne Udd: Distal myopathies and myofibrillar myopathies


• 28: Gianina Ravenscroft, Nigel F. Clarke, and Nigel G. Liang: Congenital/ultrastructural myopathies


• 29: John Vissing and Mette Orngreen: Metabolic myopathies


• 30: Gerald Pfeffer and Patrick F. Chinnery: Mitochondrial cytopathies


• 31: Emma Matthews and Michael G. Hanna: Skeletal muscle channelopathies


• 32: Marianne de Visser and Anneke J. van der Kooi: Idiopathic inflammatory myopathies


• 33: Zohar Argov: Drug-induced neuromuscular disorders


• 34: Merrilee Needham and Frank Mastaglia: Endocrine myopathies


• Section 7: Acute neuromuscular consults

  About the author

  Dr David Hilton-Jones is Consultant Neurologist at the University of Oxford and John Radcliffe Hospital, Oxford UK and Clinical Director, Muscular Dystrophy Campaign Muscle and Nerve Centre. Dr Hilton-Jones developed an interest in muscle diseases when working for Dr John Morgan-Hughes at Queen Square, London before spending a year training with the late Professor George Karpati in Montreal. He was appointed as a consultant neurologist in Oxford, UK with the intention of developing services for patients with neuromuscular disorders and is now Clinical Director of the Oxford Muscle & Nerve Centre, supported by the Muscular Dystrophy Campaign. He is also Clinical Director of the Oxford Myasthenia Centre, supported by the Myasthenia Gravis Association. His major interest is in combining clinical practice and research.
  
  Dr Martin R. Turner is a Consultant Neurologist and Senior Clinician Scientist within the Oxford University Nuffield Department of Clinical Neurosciences. His research focuses on understanding the variation in the clinical presentations of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) and finding biomarkers for them. In particular Dr Turner is interested in the role of the brain in ALS/MND, and using advanced neuroimaging to explore structure and function through his affiliation with the Oxford Centre for the Functional Magnetic Resonance Imaging of the Brain: FMRIB.

  Summary

  Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuromuscular Disorders covers the scientific basis, clinical diagnosis, and treatment of neuromuscular disorders with a particular focus on the most clinically relevant disorders. The book is organized into seven sections, starting with the general approach to the patient with neuromuscular disorders and then focusing on specific neuromuscular conditions affecting the peripheral nervous system from its origins at the spinal cord anterior horn on its outward course to their effector muscles and the inbound sensory pathways. Chapters on specific neuromuscular conditions are illustrated with typical case histories and their presenting features, allowing readers to put rarer conditions into their clinical context more easily. The concurrent online version allows access to the full content of the textbook, contains links from the references to primary research journal articles, allows full text searches, and provides access to figures and tables that can be downloaded to PowerPoint®.
  This textbook will serve as a useful reference for neurologists and specialist trainees in neurology, neuroscientists, neurophysiologists, and other healthcare professionals.

Product details

• Authors: David (Consultant Neurologist Hilton-Jones, Turner Hilton-Jones
• Assisted by: David Hilton-Jones (Editor), David (Consultant Neurologist Hilton-Jones (Editor), Martin Turner (Editor), Martin R. Turner (Editor), Martin R. (Consultant Neurologist Turner (Editor)
• Publisher: Oxford University Press
• Languages: English
• Product format: Hardback
• Released: 01.05.2014
• EAN: 9780199698073
• ISBN: 978-0-19-969807-3
• No. of pages: 400
• Series: Oxford Textbooks in Clinical Neurology
• Subject: Natural sciences, medicine, IT, technology > Medicine