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The Human Genome in Health and Disease explores the intimate link between sequence information and biological function. A range of sequence-based functional units of the genome are discussed and illustrated with inherited disorders and cancer.
List of contents
1. Introduction
2. A Molecular Disorder
3. A Code of Life
4. The Genome
5. Variants in the Human Genome Sequence and Their Biological Significance
6. The Critical Protein Coding Sequences
7. Triplet Repeats and Neurodegenerative Disorders
8. The Untranslated Parts of a Message
9. Exons, Introns, and a Royal Bleeding Disorder
10. The Regulation of Transcription
11. The Noncoding RNAs
12. Computational Methods Are Critical in the Analysis of Molecular Sequences
13. Diagnosing the Genome
14. Correcting Genome Errors
15. Epilogue
Appendixes
Glossary
Recommended Textbooks for Further Reading
Index
About the author
Tore Samuelsson
Summary
The Human Genome in Health and Disease explores the intimate link between sequence information and biological function. A range of sequence-based functional units of the genome are discussed and illustrated with inherited disorders and cancer.
