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Strategies for Overcoming Chemotherapy Resistance in Cervical Cancer: From Molecular Insights to Precision Solutions, Volume 21 highlights different strategies to reverse chemotherapy resistance in cervical cancer. The book puts a strong focus on strategies to reverse chemotherapy resistance as well as strategies for early detection of the resistance, enhancing precision oncology in terms of patient care and maximizing patient management. The book also looks at virally induced resistance to chemotherapy and recommends combination therapies that can maximize the reversal of this resistance.
In 10 chapters, the book not only gives an overview of cervical cancer and chemotherapy as treatment, but also investigates resistance to chemotherapy and treatment for resistance. It defines treatment mechanisms, options, and limitations to beat chemotherapy resistance and the reversal of the resistance mechanisms. It gives insights into future directions of cervical cancer treatment using epigenetic silencing, chemotherapy splicing, the involvement of MicroRNAs to chemotherapy resistance, and the application of Artificial Intelligence.
List of contents
1. An Overview of Cervical Cancer, chemotherapy as treatment and resistance
2. Current Treatment Options and Limitations of Cervical Cancer
3. Radiotherapy treatment resistance in cervical cancer
4. Mechanisms of Resistance in Cervical Cancer
5. Reversal of Resistance Mechanisms in Cervical Cancer
6. HPV and HIV-Associated epigenetics silencing in cervical cancer: Targets for overcoming chemoresistance
7. Splicing-Associated Chemotherapy Resistance in cervical cancer: Targeting splicing signatures
8. MicroRNAs involvement in cervical cancer chemotherapy drug resistance: restoring sensitivity to chemotherapy drugs
9. Future Directions in Cervical Cancer Treatment
10. Concluding Insights and Pathways to Overcome Cervical Chemoresistance
About the author
Zodwa Dlamini is a Professor of Molecular Oncology and the founding Director and the Executive Head of the Pan African Cancer Research Institute (PACRI) in South Africa. She is the Director of South African Medical Research Council (SAMRC) Precision Oncology Research Unit (PORU). She is the DSI/NRF SARChI Chair in Precision Oncology and Cancer Prevention (POCP). She is a member of the American Association for Cancer Research (AACR) Advisory Group on Sub-Saharan Africa. She is a member of the AACR Pathology Resources in Africa Advisory Group. Professor Dlamini is a member of the African Organisation for Research and Training in Cancer (AORTIC) Research Committee Scientific Advisory Board. She is an elected member of the Academy of Science of South Africa. Professor Dlamini is an overseas Fellow of the Royal Society of Medicine (London). She is the Associate Editor for Frontiers in Oncology: Cancer Genetics Section
