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Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics.
The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics.
The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.
List of contents
1. Introduction and Definitions
2. What Is Translational Medicine?
3. Tools
4. Biomarkers
5. Early Clinical Trial Design
6. Pharmaceutical Toxicology
7. Translational Science Biostatistics
8. Intellectual Property Rights in Translation
9. Translational research in the Elderly
10.The View of Big Pharma
11. Translational Science in Medicine: Putting the Pieces Together
12. Biomarkers, Early Human Trials, Networking, Translatability Assessment
13. Learning by Experience: Examples of Translational Processes in the Cardiovascular Field
About the author
Martin Wehling is the Managing Director at the Institute of Experimental and Clinical Pharmacology and Toxicology. Martin Wehling is Director in Clinical Pharmacology at Mannheim Medical Faculty, Mannheim University of Heidelberg, Mannheim, Germany.
Report
"This is an easy to read resource for biomedical scientists interested in the current and evolving approach to integrating various scientific approaches to answer questions important for the diagnosis and treatment of human disease. Score: 86 - 3 Stars" --Doody's
