Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approachesfor Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approachesfor Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry.

List of contents

1. Green synthetic approaches for biologically relevant heterocycles: An overview
2. Synthesis of bioactive five- and six-membered heterocycles catalyzed by heterogeneous supported metals
3. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes
4. Metal-catalyzed routes for the synthesis of furocoumarins and coumestans
5. Green solvents for eco-friendly synthesis of bioactive heterocyclic compounds
6. Green catalytic synthesis of heterocyclic structures using carbon dioxide and related motifs
7. Synthetic approaches to small and medium size aza-heterocycles in aqueous media
8. Green synthetic approaches for biologically relevant 2-amino-4H-pyrans and 2-amino-4H-pyran-annulated heterocycles in aqueous media
9. Sustainable synthesis of benzimidazoles, quinoxalines and congeners
10. Green and catalytic methods for ¿-lactone synthesis
11. Green synthetic approaches for medium ring-sized heterocycles of biological interest
12. Organocatalyzed Biginelli reactions: A greener chemical approach for the synthesis of biologically active 3,4-dihydropyrimidin-2(1H)-ones/-thiones
13. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest
14. Organo hypervalent iodine reagents in the synthesis of bioactive heterocycles
15. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds
16. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles
17. Ionic liquids prompted synthesis of biologically relevant five and six-membered heterocyclic skeletons: An update
18. Heterocycles-based ionic liquid-supported synthesis of small organic molecules
19. Microwave-induced synthesis of heterocycles of medicinal interests
20. Application of microwave irradiation in the synthesis of P-heterocycles
21. Use of ultrasound in the synthesis of heterocycles of medicinal interest

About the author

Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master’s in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari’s group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series ‘Natural Product Drug Discovery’. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).

Product details

• Assisted by: Goutam Brahmachari (Editor), Brahmachari Goutam (Editor)
• Publisher: Elsevier
• Languages: English
• Product format: Hardback
• Released: 12.11.2014
• EAN: 9780128000700
• ISBN: 978-0-12-800070-0
• Dimensions: 216 mm x 276 mm x 33 mm
• Weight: 1990 g
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Inorganic chemistry; SCIENCE / Chemistry / Inorganic, Inorganic Chemistry