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Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of omics-driven advances across different aspects of exercise and sports physiology, biochemistry, sports medicine, psychology, anthropology, and sports nutrition; and highlighting the opportunities towards advance personalized training and athlete health management. More than 70 international experts from 14 countries have discussed key exercise and sport-related themes through the prism of genomics, epigenomics, transcriptomics, proteomics, metabolomics, telomere biology, talent in sport, individual differences in response to regular physical activity, that in the future may empower coaches, sports physicians, fitness experts, genetic counselors, and translational scientists to employ various omics data and approaches in improving health and physical performance of people participating in sports and exercise activities.
Contributors address current knowledge of genetic influence on athletic performance, individual responses to exercise training, as well as the genetics of musculoskeletal phenotypes, exercise-related injuries, flexibility, and neurodegenerative disorders in athletes.
Finally, performance-related and psychological traits associated with epigenetic, transcriptomic and metagenomic biomarkers are also considered, along with nutritional and pharmacogenomic aids in sports medicine and personalized nutrition.
List of contents
SECTION I. SPORTS GENETICS1. Introduction to genetics of sport and exercise
2. Heritability estimates of physical performance-related phenotypes
3. Genes and power athlete status
4. Genetic profile of elite endurance athletes
5. Genetics of team sports
6. Variation of Mitochondrial DNA and elite athletic performance
7. Psychogenetics and sport
SECTION II. EXERCISE GENETICS AND MOLECULAR PHYSIOLOGY8. Genes and response to aerobic training
9. Effect of gene polymorphisms on sensitivity to resistance training
10. Exercise and DNA methylation in skeletal muscle
11. Genes and individual responsiveness to exercise-induced fat loss
SECTION III. GENETICS OF MUSCULOSKELETAL EXERCISE-RELATED PHENOTYPES12. Genetic and epigenetic determinants of muscle mass
13. Genetics of flexibility
14. Genetics of muscle fiber composition
SECTION IV. GENETICS OF SPORT-RELATED DISEASES AND MEDICAL CONDITIONS
15. Genetics of musculoskeletal soft tissue injuries: Current status, challenges, and future directions
16. Genetics of sport-related concussion
17. The genetic association with exercise-induced muscle damage and muscle injury risk
SECTION V. NUTRIGENETICS, PHARMACOGENETICS AND METABOLOMICS IN SPORT AND EXERCISE 18. Personalized sports nutrition: Role of nutrients in athletic performance
19. Metabolomics and proteomics as tools to advance the understanding of exercise responses: The emerging role of gut microbiota in athlete health and performance
20. The future of genetically based nutritional and pharmacological ergogenic aids in sport
21. Perspectives of personalized weight loss interventions based on exercise genomics, nutrigenetic, epigenetic, and metagenomic data in fitness and sport
About the author
Dr. Debmalya Barh is currently a Visiting Full Professor (Titular, Grade-E) in Bioinformatics and Precision Health at the Department of Genetics, Ecology, and Evolution, ICB, Federal University of Minas Gerais, Brazil and honorary scientist of the Institute of Integrative Omics and Applied Biotechnology (IIOAB), India. With over 20 years of experience, he has led academic, healthcare, molecular diagnostic, and bioinformatics industry endeavors. He works with more than 400 scientists from 100+ top ranked organizations across 40+ countries and has 220+ publications and a branded editor for 10+ cutting-edge omics related reference books. He is an expert in in precision/personalized health and integrative omics-based biomarker and target discovery in infectious and complex lifestyle diseases.Senior lecturer in Genetics and Epigenetics of the Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, UK. He worked for 15 years in the top research centers of sport science in Russia, collected DNA samples of more than 8000 professional athletes, and published over 150 peer-referred research papers in journals. Dr. Ahmetov’s main research areas include exercise and sports genomics, exercise biochemistry and physiology, behavioral genetics, nutrigenetics, sports medicine, and genetics of obesity. His group was the first to publish a genome-wide association study on athletic performance. Dr. Ahmetov is a member of the Steering Committee of the Athlome Consortium. In addition, he is an associate editor of the journal Biology of Sport.
