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Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation.
List of contents
1. Scientific rationale for designing controlled drug delivery systems
2. Current developments in excipient science: Implication of quantitative selection of each excipient in product development
3. Fundamentals of polymers science applied in Pharmaceutical Product Development
4. Use of polymers in controlled release of active agents
5. Co-polymers and block co-polymers in drug delivery and therapy
6. Pharmaceutical and biomedical applications of polymers
7. Levels of Drug targeting
8. Ligands for targeted drug delivery and applications
9. Transportation and bio interaction Properties in nanomaterials across biological systems
10. Importance of preliminary characterisation of nanoparticles in pharmaceutical product development
11. Biodegradable Block Copolymers and Their Applications For Drug Delivery
12. Bio-Nanotechnology in pharmaceutical research
13. Design and evaluation of ophthalmic delivery formulations
14. Design and fabrication of Brain targeted drug delivery
15. Cutaneous and transdermal drug delivery: Techniques and Delivery systems
16. Protein/peptide drug delivery systems: Practical considerations in Pharmaceutical Product Development
17. Nanocarriers in different preclinical and clinical stages
18. Clinical aspects and regulatory requirements for nanomedicines
About the author
Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.
