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Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism.
Changes to this edition include new chapters focused on hypercalcemia/hypocalcemia and the interaction of dialysis, chronic renal disease, and endocrine diseases. All chapters have been updated to include more preclinical data and more tables and schema that help translate this data into clinical recommendations. The section on hormones and renal insufficiency discusses insulin/diabetes, growth hormone, sex steroids, thyroid hormone, acid-base disturbances, and pregnancy.
List of contents
Part 1: The Kidney as an endocrine organ
Section 1: Erythropoietin
Section 2: Vitamin D, PTH and Novel Regulators of Phosphate
Section 3: Renin-angiotensin
Part 2: The Kidney as a Hormonal target
Section 4: Anti-diuretic hormone
Section 5: The Atrial Naturetic Peptides
Section 6: Aldosterone
Section 7: Endocrine Disorders in Renal Failure
About the author
Dr. Singh has led groundbreaking studies in anemia of kidney disease, including the CHOIR study, which was published in the New England Journal of Medicine, and well as being a member of the steering committees for the TREAT and DRIVE studies. More recently, he has taken on the role of leading the ASCEND Clinical development program - a phase 3 program for the development of a novel propyl hydroxylase inhibitor Daprodustat. The trial is aiming to recruit 7500 patients in over countries. He currently leads the office of Postgraduate Medical Education at the Brigham and Women's Hospital, and in this capacity leads several HMS CME courses. He is the author of over 160 original contributions and review articles, as well as author/editor of 11 books in internal medicine and nephrology. Dr. Singh is a Fellow of the Royal College of Physicians in London, and has an MBA from Boston University.Dr. Gordon H. Williams is an endocrinologist in Boston, Massachusetts and is affiliated with Brigham and Women's Hospital. He received his medical degree from Harvard Medical School and has been in practice for more than 30 years. He has published ~300 papers, is a well-respected and well-known expert, speaker and leader in the field of endocrinology.
