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Handbook of Amygdala Structure and Function, Volume 26, provides an updated overview on the functional neuroanatomy of amygdala nuclei, with an emphasis on interconnections (basolateral, central amygdala, medial amygdala) and their integration into related networks/circuits (prefrontal cortex, bed nucleus, nucleus accumbens). The design of this volume builds upon the foundations of functional neural circuits and the corresponding (cellular) electrophysiology important for the homeostatic control of amygdala function. This volume contains a dedicated section on the anatomical organization of the amygdala nuclei, emphasizing the role of neurotransmitters and neuropeptides that integrate signals and regulate behavior.
Additional chapters discuss cellular physiology, plasticity and the integration of electrical signals that contribute to neural activity. The final section of the book connects the role of amygdala dysfunction and the development of disorders in human health and disease.
List of contents
1. Functional Neuroanatomy of the Basolateral Amygdala: Neurons, Neurotransmitters, and Circuits
2. The Medial Amygdala: Structure and Function
3. Amygdala Neuron Subtypes Based on Genetics, Physiology and Anatomy
4. Amygdala physiology in pain
5. Neural Plasticity of the Amygdala
6. Plasticity of amygdala neurons underlying fear learning and extinction
7. Neuropeptide Y and Amygdala Circuitry: Modulation of Stress Behaviors
8. The Amygdalar Opioid System
9. Noradrenergic Regulation of the Basolateral Amygdala
10. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) in Stress, Pain, and Learning
11. Protect and Harm - Effects of Stress on the Amygdala
12. Sex Differences in Amygdala Structure and Function: From Rodents to Humans
About the author
Janice H. Urban is Professor and Chair of the Discipline of Physiology and Biophysics and Director for the Center for the Neurobiology of Stress Resilience and Psychiatric Disorders at the Chicago Medical School/Rosalind Franklin University of Medicine and Science in North Chicago, Illinois. Dr. Urban completed her graduate training in the department of Pharmacology at Loyola University Chicago and post-doctoral work at the University of Washington and Northwestern University. Dr. Urban’s research focuses on understanding the cellular and molecular mechanisms underlying stress responses and the development of stress resilience. Most recently, her work examines the role of neuropeptide Y (NPY) receptors in generating resilience through modulation of neural circuits in the amygdala.Dr. Rosenkranz graduated from the University of Pittsburgh in 1997. He remained at the University of Pittsburgh to earn the M. S. degree in 1999 and the PhD in 2002, both in Neuroscience. Following postdoctoral work at the Baylor College of Medicine and University of Texas-Austin he joined the faculty of the Department of Cellular and Molecular Pharmacology of the Chicago Medical School in 2007.
