Read more
Biomaterials for Precision Cancer Medicine bridges the gap between materials science and medicine, providing insights into novel biomaterial-based treatments for cancer. The book describes the various smart biomaterial-based treatments available, reviewing how they can be designed to target specific tumor types, adapt to changes in the cell microenvironment and offer smart, personalized therapy for different cancer variants, especially those which are drug-resistant. The book provides a materials-focused look at precision cancer medicine, and is thus useful to materials scientists, biomedical engineers, and biomedical scientists - including cancer and genetic specialists - with an interest in alternative cancer therapies.
List of contents
1. Introduction to cancer
2. Cancer therapy in the era of precision medicine
3. Precision medicine: Aspects in translational medicine
4. Biomaterials: Fundamentals, processing, and applications
5. Possible targets for biomaterials in cancer treatment
6. Biomaterials-based cancer diagnostics: Recent advances
7. Anti-cancer biomaterials: A special design for precision medicine
8. Natural plant-derived anti-cancer biomaterials
9. Combination cancer therapy by bio-macromolecules and small molecules
10. Biomaterials for cancer immunotherapy
11. Biomaterials for engineering tumor microenvironment
12. Biomaterials for cancer targeted drug delivery
13. Engineered smart biomaterials for anti-cancer gene delivery
14. Biofunctionalization of materials for targeting cancer cells
15. Reactive oxygen species (ROS)¿responsive materials in cancer therapy
16. Natural polymers for diagnosis and treatment of cancers
17. Synthetic polymers for malignancies treatment
18. Polymer-protein and polymer-drug conjugates in cancer therapy
19. Magnetic calcium phosphates for imaging and treating of cancers
20. Hydroxyapatite nanoparticles as anti-cancer agents
21. Bioactive magnetic glass-ceramics for cancer treatment
22. Mesoporous glasses in cancer therapy
23. Carbon biomaterials for cancer therapy: opportunities and challenges
24. Metals and metal compounds for cancer photothermal therapy
25. Smart nanoparticles for the treatment of drug-resistant tumors
26. Managing malignancies by magnetic electrospun nanofibers
27. Multiparametric preclinical assessment of theranostics materials
28. Health risk assessment of anti-cancer biomaterials
29. Future perspectives and challenges for biomaterials
About the author
Saeid Kargozar is a Fellow of the University of Texas Southwestern Medical Center (UTSW), USA. He was previously a Senior Assistant Professor of Tissue Engineering in the Department of Anatomy and Cell Biology, at Mashhad University of Medical Sciences in Iran. He received his M.S. in Medical Biotechnology in 2012 and his Ph.D. in Tissue Engineering in 2016, both from Tehran University of Medical Sciences, Iran. His current research interests include biocompatible materials and tissue engineering with special focus on bioactive glasses and the decellularized extracellular matrix (ECM). He is an active member of the American Ceramic Society and has published more than 118 peer-reviewed publications. According to a recent scientometric study published in PLOS Biology in 2021, he is listed amongst the top 2% of cited scientists in the world.
Dr. Masoud Mozafari is a Fellow at Lunenfeld Tanenbaum Research Institute, Mount Sinai Health Hospital, University of Toronto. He was previously Assistant Professor and Director of the Bioengineering Lab, at the Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Cellular and Molecular Research Center, and Department of Tissue Engineering and Regenerative Medicine of the Iran University of Medical Sciences (IUMS), Tehran, Iran. Dr. Mozafari’s research interests range across biomaterials, nanotechnology, and tissue engineering, and he is known for the development of strategies for the treatment of damaged tissues and organs, and controlling biological substances for targeted delivery into the human body. Dr. Mozafari has received several awards, including the Khwarizmi Award and the Julia Polak European Doctorate Award for outstanding translational research contributions to the field of biomaterials. He has also received the WIPO Medal for Inventors from The World Intellectual Property Organization (WIPO), in recognition of his contributions to economic and technological development. Dr. Mozafari is currently working on the editorial board of several journals.
