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Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects. New and contemporary methods of synthesis are discussed, with a special focus on green, environment-friendly procedures. Discussion of stereochemical studies, particularly on natural molecules, are included. Computational chemistry has emerged as an integral tool for drug discovery, hence this book explains how the drug candidate is established as suitable for clinical trials with the help of molecular docking and virtual screening modeling.
This book offers a broad range of recent developments and detailed coverage of synthesis and biological activities of the drugs, and is an ideal reference guide to researchers working in organic and medicinal chemistry.
List of contents
1. Introduction
2. Oxazoles
3. Isoxazoles
4. Bioactive Benzoxazole
5. Oxadiazole
6. Oxazolidine
7. Oxazolidinone
8. Oxazoline
9. Oxazolone
10. Conclusion
About the author
Erum Akbar Hussain studied Chemistry and received her PhD in 2002 from ICCB, H.E.J Research Institute of Chemistry, University of Karachi, Pakistan. At present, she is Tenured Associate Professor at Lahore College for Women University. Her research is focused on understanding hetero annulation reactions under the umbrella of green chemistry.Ambreen Ghani is working as Assistant Professor at University of Education, Division of Science and Technology, Lahore, Vehari Campus. She has earned PhD in 2018 from Lahore College for Women University Lahore. Her research interests include the design and synthesis of selective anti-inflammatory agents.Zubi Sadiq is currently working as a Research Associate at Lahore College for Women University, Lahore, Pakistan. She received her Ph.D. in Chemistry (2019) from same University. She received a gold medal and academic roll of honour in her MS degree. She was a lecturer of Chemistry (2012 - 2013) at Preparatory Year Deanship, King Faisal University, Al-Ahsa, Saudi Arabia. Her research interests encompass various areas of synthesis and sustainable Chemistry.
