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Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics.
In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.
List of contents
Section I: Physico-chemical aspects of dosage forms1. Physico-chemical factors influencing drug degradation
2. Stability and accelerated stability studies of dosage forms
3. Solubility of drugs
4. Drug dissolution studies of pharmaceutical formulations
5. Pharmaceutical granulation: Engineering perspective and futuristic trends
6. Tablet compression and consolidation: Theory and applications
Section II: Biopharmaceutics7. Introduction to Biopharmaceutics
8. Gastrointestinal absorption of drugs
9. Routes of drug administration and their impact in biopharmaceutics
10. Drug elimination and renal excretion of drugs
11. Membrane transport and permeation of drugs
12. Factors affecting drug absorption and disposition
13. Bioavailability and bioequivalence
14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy
15. Dosage regimen
16. Multicompartment models
17. Nonlinear pharmacokinetics
18. Computer-aided biopharmaceutical model development
19. Computer simulations in pharmacokinetics
20. WHO and ICH Guidelines for ‘Good Manufacturing Practices’
21. Pilot plant scale up techniques in pharmaceutical product development
22. Advances in solid dosage forms
About the author
Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.
Dr. Kalyan Kumar Sen (MPharm, PhD) has over 38 years of teaching and industrial and research experience in the field of pharmaceutics, especially in the development and characterization of novel drug delivery systems. He has earned his PhD in pharmacy from Jadavpur University, India. Currently, Dr. Sen is working as a principal and professor of Gupta College of Technological Sciences, Asansol, India. Till date, he has authored several publications in various journals of international repute. He has authored several book chapters. He already has edited two books and co-authored one book. He has been the permanent reviewer of many international journals of high repute. Dr. Sen has participated and presented his research work at several conferences in India. Dr. Sen is a life member of the APTI and several professional bodies.
