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List of contents
Section A: Assay and Exposure Technology.- Session I: Assay and Exposure Technology of In Vitro Microbial Assay Systems Applied to Airborne Agents.- An Exposure System for Quantitative Measurements of the Microbial Mutagenicity of Volatile Liquids.- Review of Fractionation and Bioassay Characterization Techniques for the Evaluation of Organics Associated with Ambient Air Particles.- Airborne Particle Collection and Extraction Methods Applicable to Genetic Bioassays.- Session II: Assay and Exposure Technology of In Vitro Mammalian Cell Systems Applied to Airborne Agents.- In Vitro Analysis of Mammalian Cells Exposed In Vitro and In Vivo to Airborne Agents.- Methods for Detecting Gaseous and Volatile Carcinogens Using Cell Transformation Assays.- CHO/HGPRT Mutation Assay: Evaluation of Gases and Volatile Liquids.- Lung Cells Grown on Cellulose Membrane Filters as an In Vitro Model of the Respiratory Epithelium.- Session III: Plant Bioassays for the Detection of Airborne Genotoxic Agents.- Monitoring Ambient Air for Mutagenicity Using the Higher Plant Tradescantia.- Environmental Clastogens Detected By Meiotic Pollen Mother Cells.- Plant Genetic Systems with Potential for the Detection of Atmospheric Mutagens.- Session IV: Animal Exposure Technology for the Detection of Genotoxic Agents.- Systems for Exposure of Animals to Airborne Agents.- Techniques for the Generation and Monitoring of Vapors.- Problems Associated with Assessing the Mutagenicity of Inhalable Particulate Matter.- Section B: Airborne Agents.- Session V: Benzene.- An Overview of the Problem of Benzene Toxicity and Some Recent Data on the relationship of Benzene Metabolism to Benzene Toxicity.- Benzene Metabolites: Evidence for an Epigenetic Mechanism of Toxicity.- Cytogenetic Effects of Inhaled Benzene in Murine Bone Marrow.- Benzene Leukemogenesis.- Session VI: Organic Halides C. Maltoni Moderator.- Genetic Effects of Ethylene Dibromide in Drosophila Melanogaster.- Mutagenic and Oncogenic Effects of Chloromethanes, Chloroethanes and Halogenated Analogues of Vinyl Chloride.- Vinyl Chloride: A Model Carcinogen for Risk Assessment.- Session VII: Miscellaneous Agents.- Inhalation Anesthetics.- Mutagenic and Carcinogenic Effects of Formaldehyde.- The Microbial Mutagenicity of Nitroarenes.- Mutagenic Effects in Human and Mouse Cells by a Nitropyrene.- Genotoxic Properties of Radon and Its Daughters.- Multiple Tissue Comparisons of Sister Chromatid Exchanges Induced by Inhaled Styrene.- An Overview of Ethyl Carbamate (Urethane) and Its Genotoxic Activity.- Section C: Monitoring and Risk Assessment.- Session VIII: Monitoring of Human Populations At Risk.- Cytogenetic Monitoring of Human Populations.- Thioguanine Resistent Lymphocytes As Indicators of Somatic Cell Mutation in Man.- Detection of Point Mutations in Mammalian Sperm.- Session IX: Extrapolation of Genotoxic Data To Human Health Effects.- Extrapolation of Laboratory Data to Human Health Effects.- Molecular Dosimetry as a Bridge Between Mammalian and Non-Mammalian Test Systems.- Is Radiation an Appropriate Model for Chemical Mutagenesis and Carcinogenesis?.- Session X: Regulatory Risk Assessment.- Impact of Energy and Pollution on Public Health.- Policy and Procedures for Using Mutagenicity Data in Assessing Genetic Risk.- The Sensitivity of Method Procedure as a Regulatory Mechanism for Approval of Carcinogens.- Contributed Papers.- The Human Genetic Risk of Airborne Genotoxics: An Approach Based on Electrophoretic Techniques Applied to Mice.- Photon-Emitting Microorganisms as Test Objects for Detecting Genotoxic Agents.- Detection of Genotoxic Airborne Chemicals in Rat Liver Culture Systems.- The Induction of Sister Chromatid Exchange in Human Lymphocytes and Bacterial Mutagenesis by Organic Extracts of Urban Airborne Particles.- An epidemiological Study of Cancer Deaths in Pathfor, Kentucky.- List of Participants.- Agent Index.
