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This collection provides detailed information on current advances in analytical methods and strategies employed for monitoring and discovering a wide range of novel psychoactive substances (NPS) in clinical and forensic laboratories. The main classes of NPS in terms of prevalence include synthetic cannabinoids, synthetic cathinones, synthetic opioids, and designer or synthetic benzodiazepines, and this book explores selecting the appropriate sample matrix and analytical testing approaches for laboratories faced with NPS drug testing, such as in blood, urine, saliva, and hair. Written for the Methods in Pharmacology and Toxicology series, chapters in this volume feature the kind of detailed implementation advice from the experts that leads to successful results in the lab.
Authoritative and practical, Methods for Novel Psychoactive Substance Analysis serves as an ideal guide for forensic and clinical toxicologists, pharmacologists and chemists inacademic and research settings, as well as for private laboratories seeking to increase our ability to test for these substances.
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List of contents
Introduction/Overview.- Target analysis of synthetic cannabinoids in blood and urine.- Target analysis of synthetic cathinones in blood and urine.- Target analysis of phenethylamines, piperazines and tryptamines in blood and urine.- Target analysis of synthetic opioids in blood and urine.- Target analysis of synthetic benzodiazepines in blood and urine.- Target analysis of NPS in alternative matrix hair.- Target analysis of NPS in alternative matrix oral fluid.- Target analysis of NPS in other alternative matrices (dried blood spots, meconium).- Target analysis of NPS in postmortem samples.- High Resolution Mass Spectrometry in NPS qualitative analysis.- High Resolution Mass Spectrometry in NPS quantitative analysis.- High Resolution Mass Spectrometry in identification of new analytes & metabolites.- Alternative NPS screening approaches for high-throughput laboratories.
