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This multivolume work is the only comprehensive, up-to-date reference work on the theory, occurrence and application of hydrogen transfer processes. Adopting an integrated approach, this handy reference includes essential information on the theoretical basis, the fundamental types, and the latest techniques used to reveal, monitor, as well as measure hydrogen transfer reactions. Renowned experts from a number of disciplines provide a thorough overview on all aspects of hydrogen transfer in natural and artificial systems, thus aiding readers in their own research. Numerous tables and illustrations facilitate fast and easy access to the desired information, making this an indispensable source of knowledge for every research group working in the field.
List of contents
PART 1Prototropic rearrangementsHydrogen transfer in the gas phaseHydrogen transfer in liquids and solidsHydrogen isotope effects and transition-state structureQuantum theoretical treatments of hydrogen transferPrinciples of hydrogen transfer in solutionMultiple isotope effects as diagnostic tools of mechanismNMR Methods in the study of hydrogen transferHydrogen transfer in iceHydrogen bonding and hydrogen transferHydrogen transfer in designed catalystsHydrogen-atom transfer in solutionPART 2Proton transfer in solution reactionsTheory of proton transfer in enzymic and model reactionsModel reactions for enzymic hydride transferProton transfer in enzymic acid-base catalysisProton conduction in enzyme actionHydrogen bonding and enzyme catalysisPrototropic rearrangements in enzymic systemsProton transfer in thiamin activation and other enzymic C-H fissionsProton transfer and protein foldingQuantum tunneling in enzymic hydrogen transferHydrogen-atom transfer in enzymic systemsHydrogen transfer and protein stability
About the author
Professor Schowen has closed his research groups, but continues to work in collaborations. Active programs include these projects:
- Studies of the mechanism, involvement of protein dynamics, and antiparasitic drug design for S-adenosylhomocysteine hydrolases
- Studies of the stability and degradation kinetics and mechanisms of peptide and protein pharmaceuticals in solution and in solid-phase, polymeric solids
- Design and characterization of green catalysts
Summary
This multivolume work is the only comprehensive, up-to-date reference work on the theory, occurrence and application of hydrogen transfer processes. Adopting an integrated approach, this handy reference includes essential information on the theoretical basis, the fundamental types, and the latest techniques used to reveal, monitor, as well as measure hydrogen transfer reactions. Renowned experts from a number of disciplines provide a thorough overview on all aspects of hydrogen transfer in natural and artificial systems, thus aiding readers in their own research. Numerous tables and illustrations facilitate fast and easy access to the desired information, making this an indispensable source of knowledge for every research group working in the field.
Report
"... eine eindrucksvolle Sammlung von kurzen Aufsätzen über Wasserstofftransferreaktionen? Es ist das große Verdienst dieses Handbuches, auf 274 Seiten erstmals das Peer-Review-Verfahren zu beschreiben..."Angewandte Chemie 2008-120/10
