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Metabolomics - which deals with all metabolites of an organism - is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.
This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
List of contents
Analytical Technology.- Gas Chromatography Mass Spectrometry.- Current Status and Forward Looking Thoughts on LC/MS Metabolomics.- Plant Metabolomics Strategies Based upon Quadrupole Time of Flight Mass Spectrometry (QTOF-MS).- Capillary HPLC.- Capillary HPLC Coupled to Electrospray Ionization Quadrupole Time-of-flight Mass Spectrometry.- NMR Spectroscopy in Plant Metabolomics.- Hetero-nuclear NMR-based Metabolomics.- Bioinformatics.- Bioinformatics Approaches to Integrate Metabolomics and Other Systems Biology Data.- Chemometrics in Metabolomics - An Introduction.- Map Editor for the Atomic Reconstruction of Metabolism (ARM).- AraCyc: Overview of an Arabidopsis Metabolism Database and its Applications for Plant Research.- KaPPA-View: A Tool for Integrating Transcriptomic and Metabolomic Data on Plant Metabolic Pathway Maps.- KNApSAcK: A Comprehensive Species-Metabolite Relationship Database.- Applications.- Systems Biology: A Renaissance of the Top-down Approach for Plant Analysis.- Systems-based Analysis of Plant Metabolism by Integration of Metabolomics with Transcriptomics.- Targeted Profiling of Fatty Acids and Related Metabolites.- Metabolic Profiling and Quantification of Carotenoids and Related Isoprenoids in Crop Plants.- Metabolomics and Gene Identification in Plant Natural Product Pathways.- Metabolomic Analysis of Catharanthus roseus Using NMR and Principal Component Analysis.- Metabolomics of Plant Secondary Compounds: Profiling of Catharanthus Cell Cultures.- The Taxus Metabolome and the Elucidation of the Taxol® Biosynthetic Pathway in Cell Suspension Cultures.- The Use of Non-targeted Metabolomics in Plant Science.- Plant Metabolite Profiling for Industrial Applications.
Summary
Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.
This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
