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Zusatztext "? is very timely! bringing readers up to date with various facets of the work being carried out. ? For an in-depth discussion of certain aspects of nitric oxide in mammalian systems! this is a very good book to read! with the excellent referencing that will allow for expanded further reading. ?" - John T Hancock! School of Biosciences! University of the West of England! U.K.! in The Quartely Review of Biology! Vol. 81! December 2006 Informationen zum Autor Santiago Lamas Klappentext This is the first comprehensive work to showcase the useful diversity of cellular effects elicited by nitric oxide. A collection of expert contributors provides cutting-edge information on a variety of topics with tremendous implications in biology and medicine. These include nitric oxide-driven cell signaling; nitric oxide's role in hypoxia! gene expression! gene regulation in pulmonary pathophysiology! cell metabolism modulation! and tumor biology; and the intriguing concept of mitochondrial nitric oxide synthase as a regulator of mitochondrial bioenergetics and free radical production. Zusammenfassung Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. This title showcases the useful diversity of cellular effects elicited by nitric oxide. Inhaltsverzeichnis Table of Contents Nitric Oxide Controls Cell Respiration by Reacting with Mitochondrial Complex IV: Paolo Sarti! Alessandro Giuffrè! and Maurizio Brunori Mitochondrial Nitric Oxide Signaling in Synaptic Plasticity and Cell Death: Alberto Boveris! Silvia Lores-Arnaiz! Juanita Bustamante! and Analía Czerniczyniec Mitochondrial Nitric Oxide and Redox Signaling Modulation of Cell Behavior: María Cecilia Carreras! Soledad Galli! Daniela P. Converso! Juan José Poderoso! and Enrique Cadenas Functions of Mitochondrial Nitric Oxide Synthase: Pedram Ghafourifar and Alfredo Saavedra-Molina Peroxynitrite: A Mediator of Nitric-Oxide-Dependent Mitochondrial Dysfunction in Pathology: Celia Quijano! Adriana Cassina! Laura Castro! Marianela Rodriguez! and Rafael Radi Modulation of Glucose Metabolism by Nitric Oxide\ in Astrocytes and Neurons: Juan P. Bolaños! María Delgado-Esteban! Pilar Cidad! Paula García-Nogales! and Angeles Almeida Nitric Oxide Cell Signaling Mediated by cGMP: Emil Martin! Iraida Sharina! Aurora Rachel Seminara! Joshua Krumenacker! and Ferid Murad Regulation of Cell Signaling by Protein Nitrosylation/Denitrosylation: Joan B. Mannick Nitric Oxide and Caspase Activation: Judith Haendeler and Stefanie Dimmeler Signaling Effects of Peroxynitrite in Mammalian Cells: Lars-Oliver Klotz Nitric Oxide and Cell Signaling: Redox Regulation of Ras Superfamily GTPases: Jongyun Heo and Sharon L. Campbell Nitric Oxide and the Hypoxia Inducible Factor-1Transducing System: Jie Zhou and Bernhard Brüne The Cross Talk between Nitric Oxide and Ceramide: Coordinate Interactions among Signaling Pathways Regulating Cell Death! Survival! and Differentiation: Cristiana Perrotta! Clara De Palma! Sestina Falcone! and Emilio Clementi S-Nitrosothiol Signaling and Gene Regulation in Pulmonary Pathophysiology: Khalequz Zaman! Lisa A. Palmer! and Benjamin Gaston Nitric Oxide and Gene Expression: Josef Pfeilschifter and Karl-Friedrich Beck Nitric Oxide as a Modifier of Gene Expression Nitric Oxide and Post-Transcriptional Control of Gene Expression by the IRE/IRP System: Leonor Oliveira! Cécile Bouton ! and Jean-Claude Drapier Nitric Oxide and Tumor Biology: Pierre Sonveaux and Olivier Feron Index ...