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Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery systems in cancer treatment. Several nanotechnological methods are presented to enhance drug solubility, sustainability, bioavailability, and gastrointestinal permeability of these phytochemicals. Current understanding of the relevant information presented on therapeutic strategies in cancer therapy fulfils the requirements of oncologists, molecular biologists, pharmacologist and related researchers who want to work in the areas of drug development targeting phytochemicals for cancer therapy.
List of contents
1. Significance of phytochemicals in cancer therapy
2. Emerging need of delivery systems for plant metabolites
3. Phytosome: A promising drug-delivery system for cancer therapy
4. Exosome-based delivery systems for natural compounds in cancer therapy
5. Potential implications of ethosomes and transethosomes to deliver phytomedicine in cancer treatment
6. Chitosan-based drug delivery of plant metabolites for the treatment of breast cancer
7. Sporopollenin-based targeted drug delivery system for gastrointestinal cancer
8. Nanotechnology based delivery system for phytochemicals in cancer therapy
9. Delivery system of phenolic compounds for the treatment of lung cancer
10. Advancement in drug delivery systems of curcumin for cancer chemoprevention
11. Drug delivery system for saponins in cancer treatments
12. Administration of plant-derived terpenoids in cancer management
13. Therapeutic role of essential oils in malignancies through drug delivery mechanisms
14. Development of codelivery system for phytochemicals and targeted siRNA in cancer therapy
15. Future challenges of drug-delivery systems for phytochemicals in cancer management
About the author
Dr. Akhileshwar Kumar Srivastava works as a Research Associate (ICMR) in CSIR-Central Food Technological Research Institute, Mysore, India. In his eight years of research, he has published approximately 20 research articles and book chapters in international and national journals of repute. His research specialization is primarily in the area of pharmacognosy with genetics, metabolomics, bioinformatics, and molecular biology-associated targeting cancer diseases. In addition, he has studied at Augusta University (formerly, Georgia Regents University) in Augusta, GA, United States on a J-1 Exchange Scholar Visa and at Ben-Gurion University, Israel. He is also a life member fellow in Indian Science Congress and Agriculture, Nutrition and Health Academy, United Kingdom.Divya Singh is presently working as Scientist-B in Department of Mulberry Physiology, CSRTI, Mysore, India. Her research specialization is primarily in genetics, proteomics, metabolomics, toxicology, bioinformatics and molecular biological evaluation in various in vivo and in vitro plant models to elucidate the physiological changes and evaluate the DNA damage potency. In her 11 years of research experiences, she has published 8-peer reviewed publications, two books (1 edited and 1 authored) including 6 book chapters and several meeting presentations at local and international scientific meetings.Dr. Rajesh Kumar Singh is currently working as a Research Associate in Banaras Hindu University. His research focus is pharmacognosy, reverse pharmacology, drug design and discovery, extraction & isolation of natural products, cell culture, and handling of different rodents. He has published several research articles in reputable journals over the course of his career. At present, he is involved in developing an Indian origin cell line and screening drugs of natural origin for the treatment of gallbladder cancer.
