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This handbook provides physicians, clinicians, and educators with the essential, reliable information they need to successfully initiate and maintain insulin therapy in people with type 1 and type 2 diabetes. Now in its sixth edition,
Practical Insulin has been revised and updated to reflect the latest American Diabetes Association Standards of Care in Diabetes.
Inside, you’ll find information about currently available insulin products, delivery methods, injection regimens, dose calculations, and more. With this guide, you can make improved glycemic control an achievable reality for the people with diabetes in your care.
List of contents
Introduction1
Insulin: Basic Physiology and Pharmacology3
Available Insulin Products7
Rapid-Acting Insulin7
Short-Acting Insulin10
Intermediate-Acting Insulin11
Long-Acting Insulin12
Insulin Glargine (U-100)12
Insulin Detemir13
Insulin Glargine (U-300)13
Insulin Degludec (U-100; U-200)14
U-500 Regular Insulin15
Premixed Insulin Products15
Insulin Administration and Use Considerations19
Insulin Delivery Method19
Vial and Syringe22
Insulin Pens22
Smart Connected Insulin Pens23
Continuous Subcutaneous Insulin Infusion
(CSII; Insulin Pump)23
Injection Technique25
Factors That May Affect Absorption26
Insulin Storage27
General Approaches and Recommendations for
Insulin Use in People with Diabetes29
Type 1 Diabetes29
Glycemic Goals and Targets in People with
Type 1 Diabetes31
Insulin Initiation and Titration32
Insulin-to-Carbohydrate (I:C) Ratios33
Correction Doses34
Ongoing Insulin Adjustment in T1D35
Type 2 Diabetes35
Sample Insulin Regimens39
Two Injections per Day39
Three Injections per Day40
Four Injections per Day, Example 141
Four Injections per Day, Example 242
Troubleshooting Barriers to Insulin Use and
Key Adverse Events45
Barriers to Insulin Use in Type 2 Diabetes45
Hypoglycemia46
Hypoglycemia Unawareness48
Weight Gain48
Adjustments for Physical Activity49
Education and Resources for People with Diabetes51
Index55
About the author
Joshua J. Neumiller, PharmD, CDCES, FADCES, FASCP, is the Vice-Chair & Allen I. White Distinguished Professor in the Department of Pharmacotherapy, College of Pharmacy and Pharmaceutical Sciences at Washington State University.
Summary
This handbook provides physicians, clinicians, and educators with the essential, reliable information they need to successfully initiate and maintain insulin therapy in people with type 1 and type 2 diabetes. Now in its sixth edition, Practical Insulin has been revised and updated to reflect the latest American Diabetes Association Standards of Care in Diabetes.
Inside, you’ll find information about currently available insulin products, delivery methods, injection regimens, dose calculations, and more. With this guide, you can make improved glycemic control an achievable reality for the people with diabetes in your care.
