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In this issue of Clinics in Laboratory Medicine, guest editor Dr. Alexa J. Siddon brings her considerable expertise to the topic of Myelodysplastic Syndromes. Top experts in the field discuss the various aspects of rare myelodysplastic syndromes and its treatments, detection, and characteristics. Topics include molecular changes in myelodysplastic syndromes; MDS with mutated SF3B1; myeloid neoplasms with mutated TP53; mimics of myelodysplastic syndromes; myeloid neoplasms with germline predisposition; and more.
- Contains 12 practice-oriented topics including premalignant clonal hematopoiesis (CHIP and CCUS); morphologic characteristics of MDS; acute leukemia arising from MDS; treatment considerations of MDS for pathologists; and more.
- Provides in-depth clinical reviews on myelodysplastic syndromes, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
List of contents
Flow Cytometric Assessment of Myelodysplastic Syndromes/Neoplasms
Molecular Techniques and Gene Mutations in Myelodysplastic Syndromes
Premalignant Clonal Hematopoiesis (Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance)
Morphologic Characteristics of Myelodysplastic Syndromes
Significance of SF3B1 Mutations in Myeloid Neoplasms
Diagnosis and Classification of Myelodysplastic Syndromes with Mutated TP53
Germline Predisposition to Myeloid Neoplasms: Diagnostic Concepts and Classifications
Childhood Myelodysplastic Syndrome
Acute Myeloid Leukemia Arising from Myelodysplastic Syndromes
Transfusion Support of Patients with Myelodysplastic Syndromes
Treatment Considerations of Myelodysplastic Syndromes/Neoplasms for Pathologists
