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Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. Using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. The growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.
List of contents
1 Basic Concepts in Molecular Pathology.- 2 Genetic Inheritance.- 3 Mutation.- 4 Methods in Molecular Pathology.- 5 Inherited Disorders.- 6 Molecular Origins of Cancer.- 7 Familial Cancer Syndromes.- 8 Molecular Pathology of Hematological Malignancies.- 9 Pharmacogenetics.- 10 Identity Testing.- 11 Molecular Diagnoses of Human Immunodeficiency Virus and Hepatitis C Virus.
Summary
Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. Using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. The growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.
Additional text
"...nicely summarizes a broad and rapidly growing diagnostic field...This is a useful introduction to molecular pathology for a wide variety of individuals. I'd recommened it to those seeking broad, concise (but not necessarily comprehensive), and current information in this field." -Doody's Health Sciences Book Review Journal
"...a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge...illuminates for every pathologist, pathology resident, physician, and medical student the ongoing molecular revolution that is now transforming pathology and the practice of laboratory medicine." -Tumori
"...this book would make a welcome and timely addition to laboratory libraries...provide(s) a great service to and an excellent reference for molecular pathologists." - Clinical Chemistry
Report
"...nicely summarizes a broad and rapidly growing diagnostic field...This is a useful introduction to molecular pathology for a wide variety of individuals. I'd recommened it to those seeking broad, concise (but not necessarily comprehensive), and current information in this field." -Doody's Health Sciences Book Review Journal
"...a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge...illuminates for every pathologist, pathology resident, physician, and medical student the ongoing molecular revolution that is now transforming pathology and the practice of laboratory medicine." -Tumori
"...this book would make a welcome and timely addition to laboratory libraries...provide(s) a great service to and an excellent reference for molecular pathologists." - Clinical Chemistry
