Candace Pert - Genius, Greed, and Madness in the World of Science

"Candace Pert stood at the dawn of three revolutions: the women's movement, integrative health, and psychopharmacology. A scientific prodigy, she was 30 years ahead of her time, preaching a holistic, interdisciplinary approach to healthcare and medicine long before yoga hit the mainstream and 'wellness' took root in our vernacular. Her bestselling book Molecules of Emotion made her the mother of the Mind/ Body Revolution, launching a paradigm shift in medicine. Deepak Chopra credits her with creating his career, and he said as much in his eulogy at her funeral. Candace began her career as an unbridled maverick. In 1972, as a 26-year-old graduate student at Johns Hopkins, she discovered the opiate receptor, revolutionizing her field and enabling pharmacologists to design new classifications of drugs from Prozac to Viagra to Percocet and OxyContin. The tragic irony of her breakthrough, touted as the first step to end heroin addiction, is that it helped spawn a virulent epidemic of drug dependence. Facing the largest public health crisis of the 21st century, Candace was incensed that the Hippocratic oath-'first, do no harm'-would succumb to greed, and as witness to this abuse of power, she was one of few scientists courageous enough to protest. Later, as Chief of Brain Biochemistry at the National Institutes of Health, Candace created Peptide T, the non-toxic treatment for HIV featured in Dallas Buyers Club. As the AIDS pandemic raged, triggering panic across Reagan-era America, the U.S. government poured massive amounts of money into finding a cure, sparking a battle among scientists for funding and power. Bested by rivals with competing drugs yet desperate to help, Candace went rogue, becoming a lynchpin in the black market for Peptide T. After a scandalous departure from her tenured position at the NIH, Candace launched a series of private companies with Michael Ruff, her second husband and collaborator. Naèive to the world of business, she was manipulated by investors keen to wrest control of her discoveries. But Candace too became tainted, believing that her noble ends would justify devious means. Like a mythic hero, she succumbed to a fatal flaw, and her greatest strengths-singularity of purpose and blind faith in her own virtuosity-would prove to be her undoing"--

About the author

Pamela Ryckman is a screenwriter, producer, and business executive with a focus on women in the workforce. She is the author of STILETTO NETWORK: Inside the Women’s Power Circles That Are Changing the Face of Business (HarperCollins Leadership/Amacom, 2013), which received a starred review from Publishers Weekly. Ryckman is also a thought leader and speaker who consults on diversity to global corporations. With Shaquille O’Neal and Credit Suisse, Ryckman launched Momentum: Black Men’s Leadership Retreat, which convened 50 of the nation’s most high-powered African American men in 2015 to focus on job creation and economic empowerment in the Black community.
Additionally, Ryckman has written for The New York Times, Financial Times, and Washington Post, among other publications. She was the first to shed light on Belizean Grove, a secret society of the world’s most powerful women, and she co-authored CS Gender 3000, a Credit Suisse research report that debunked the “Queen Bee” myth for women. Ryckman is an investor in Operator Collective, a venture fund that supports women and minorities, and in Lucky Godot, a theatre development fund. She is also a board member of Page 73 Productions, which won a 2020 Obie Award for providing extraordinary support for early-career playwrights and counts among its alumni two Pulitzer Prize winners and a MacArthur Fellow.
From 2003 to 2009, Ryckman was on the board of The Alliance of Resident Theatres/New York, which won a 2010 Tony Award for Excellence in the Theatre. Early in her career, Ryckman held internal strategy roles at Merrill Lynch’s Global Markets and Investment Banking Group, and at Goldman Sachs & Co.’s Equities Financial and Strategic Management group. She earned her A.B. in Comparative Literature from Princeton University and her M.A. in Journalism from NYU.

Summary

Candace Pert stood at the dawn of three revolutions: the opioid crisis, the AIDS crisis, and the mind-body movement. Indeed, her visionary work shaped history – for good and, inadvertently, for evil. 
 

Before there was Bessel van der Kolk, there was Candace Pert, the Mother of the Mind-Body Revolution. Her story forms a launchpad to discuss the most pressing issues plaguing science and healthcare today. 
Pert played pivotal roles in major movements in both science and politics. Namely, she:

• Discovered the opiate receptor (the mechanism by which opioids function in the brain), launching the opioid crisis.
  
• Proved the mind-body link, launching the field of integrative or functional medicine.
  
• Created Peptide T, the underground AIDS drug featured in the film Dallas Buyers Club, and then went rogue, becoming a linchpin in the black market for her drug.
  

Pert was sabotaged by mentors and colleagues keen to profit from her brilliance. But she too became tainted, believing that her noble ends would justify devious means. Like a mythic hero, she succumbed to a fatal flaw, and her greatest strengths—singularity of purpose and blind faith in her own virtuosity—would prove to be her undoing.
CANDACE PERT is a great read for anyone interested in integrative health, mind-body awareness, medical ethics, the bureaucracy of a toxic healthcare system, and a flawed genius whose scandals and breakthroughs shaped history. 

“Exemplary research, balanced accounts and deeply evocative prose... a truly insightful narrative on what it can mean to be a woman at the cutting edge of science.” – The Wall Street Journal
“Riveting biography… nuanced portrait…Readers will be engrossed.” – Publisher's Weekly
“There is a revolution taking form that is significantly influencing how the Western medical community views health and disease. Candace Pert’s contribution to this revolution is undeniable.” – Deepak Chopra
“Ryckman’s writing is life-like, suspenseful, and creates a roller coaster ride of stakes and unexpected discovery” – Dr. Lisa Miller, New York Times bestselling author of The Spiritual Child and The Awakened Brain

Foreword

The story of maverick scientist Candace Pert, whose groundbreaking research introduced the world to the mind-body connection, opioid receptors, and peptide T, and her fight for recognition in a toxic healthcare system.

Product details

• Authors: Pamela Ryckman, Ryckman Pamela
• Languages: English
• Product format: Hardback
• Released: 09.04.2024
• EAN: 9780306831461
• ISBN: 978-0-306-83146-1
• No. of pages: 304
• Dimensions: 158 mm x 232 mm x 30 mm
• Weight: 500 g
• Subjects: Fiction > Narrative literature > Letters, diaries; Natural sciences, medicine, IT, technology > Natural sciences (general); BIOGRAPHY & AUTOBIOGRAPHY / Women, Biography: general, MEDICAL / AIDS & HIV, HIV / AIDS, Medicine: HIV/AIDS, retroviral diseases