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"This book describes the revolutionary efforts underway to build virtual humans - from cells and organs to whole bodies and populations. Virtual human technology has extraordinary potential, but also poses enormous computational challenges. Digital doppelgèangers of patients will be able to usher in an era of truly personalized medicine, in which virtual drug trials can be conducted on thousands of digital twins, and "health-casts" can give you an idea of what a change in diet and lifestyle would really mean for you. Your "virtual you" will change your healthcare and potentially extend your lifespan (while also raising philosophical and ethical questions). However, numerous challenges and problems need to be solved to build such virtual versions of humans and to make truly personalized and predictive medicine possible. These challenges largely reside in the domains of the computer and physical sciences, and they are the real focus of this book. Building a "virtual you" touches on a wide range of deep scientific issues: how detailed the models need to be; what is currently possible to model; the problems inherent to simulating chaos and complexity; how to stitch together different kinds of mathematical models; the need for the realization of new forms of computing, such as quantum computation; and how all this relates to the limits of what we can simulate digitally and the future of computer modeling. The book ends on a provocative note, claiming that although we will be able to go far with next generation exascale and quantum computers, we will need to return to the technology of analog machines in order to simulate the complexity of the human body and perhaps harness the properties of special metamaterials to solve equations by manipulating beams of light"--
About the author
Peter Coveney is director of the Centre for Computational Science at University College London, professor at the Informatics Institute, University of Amsterdam, and adjunct professor at the Yale School of Medicine.
Roger Highfield is science director at the Science Museum Group, a member of the Medical Research Council, and visiting professor at University College London and the Dunn School, University of Oxford. They are the authors of
Frontiers of Complexity and
The Arrow of Time.
Additional text
"Computer simulations are coming to play a leading role in many fields of science. Science writer Highfield and computer scientist Coveney show in vivid examples how medical researchers are creating digital twins of individual patients and then using these virtual humans to guide treatments for a wide range of diseases.
"---Clive Cookson, Financial Times
