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Informationen zum Autor Valentin Fuster, MD, PhD, former Chairman of the American Heart Association's Committee on Vascular Lesions, Assessing and Modifying the Vulnerable Atherosclerotic Plaque explores the most cutting-edge developments in a field grown richer through technological advances. Klappentext "This Annals volume stems from the two-day conference "Evolving Challenges in Promoting Cardiovascular Health" sponsored by the New York Academy of Sciences, "la Caixa" Foundation, and the International Center for Scientific Debate (ICSD), which took place November 4-5, 2011 in Barcelona, Spain. Leading and emerging investigators working on the fields of cardiology, vascular disease, inflammation, metabolic disorders, hematology, imaging, regenerative medicine, stem cell research, epidemiology, and nutrition, among others, address novel issues, current challenges, and future directions in the prevention, treatment, and management of the evolving global epidemic of cardiovascular disease. The papers in this volume explore the promotion of cardiovascular health through molecular biology, clinical pathophysiology, and population research"--Publisher's description. Zusammenfassung This Annals volume stems from the two-day conference "Evolving Challenges in Promoting Cardiovascular Health" sponsored by The New York Academy of Sciences! "la Caixa" Foundation! and the International Center for Scientific Debate (ICSD)! which took place November 4-5! 2011 in Barcelona! Spain. Inhaltsverzeichnis 1. Cardiovascular defense challenges at the basic, clinical, and population levels Jason C. Kovacic, Jose M. Castellano, and Valentin Fuster 7. Plaque neovascularizationl defense mechanisms, betrayal, or a war in progress Pedro R. Moreno, Meeranani Purushothaman, and K-Raman Purushothaman 18. LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: inflammatory resolution versus thrombotic chaos Lina Badimon and Gemma Vilahur 33. Evolving role of molecular imaging for new understanding: targeting myofibroblasts to predict remodeling Hans J. de Haas, Susanne W. van den Borne, Hendrikus H. Boersma, Riemer H.J.A. Slart, Valentin Fuster, and Jagat Narula 42. Molecular targets in heart failure gene therapy: current controversies and translational perspectives Victor Kairouz, Larissa Lipskaia, Roger J. Hajjar, and Elie R. Chemaly 51. Engineered arterial models to correlate blood flow to tissue biological response Jordi Martorell, Pablo Santomá, José J. Molins, Andrés A. García-Granada, José A. Bea, Elazer R. Edelman, and Mercedes Balcells 57. A bird's-eye view of cell therapy and tissue engineering for cardiac regeneration Carolina Soler-Botija, Juli R. Bagó, and Antoni Bayes-Genis 66. Umbilical cord blood for cardiovascular cell therapy: from promise to fact Santiago Roura, Josep-Maria Pujal, and Antoni Bayes-Genis 71. Heart repair: from natural mechanisms of cardiomyocyte production to the design of new cardiac therapies Silvia Martin-Puig, Valentín Fuster, and Miguel Torres 82. Energy metabolism plasticity enables stemness programs Clifford D.L. Folmes, Timothy J. Nelson, Petras P. Dzeja, and Andre Terzic 90. The future: therapy of myocardial protection David Sanz-Rosa, Jaime Garcia-Prieto, and Borja Ibanez 99. The links between complex coronary disease, cerebrobascular disease, and degenerative brain disease Jason C. Kovacic, Jose M. Castellano, and Valentin Fuster 106. Optimal lipid targets for the new era of cardiovascular prevention Vimal Ramjee, danny J. Eapen, and Laurence S. Sperling 115. Controversies in blood pressure goal guidelines and masked hypertension Robert A. Phillips 123. Evolving diagnostic and progn...
