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This updated and revised textbook presents a broad overview on topics concerning cellular electrophysiology - ranging from bioelectric phenomena recognized as far back as ancient Egypt to popular topics on the dangers of electrosmog. Without sacrificing scientific precision, this clear and concise work presents on the one hand the different methods and modern applications, on the other hand the biophysical fundamentals of ion-channel and carrier proteins. Numerous and carefully selected illustrations and diagrams supplement the text. Each chapter is extended by a detailed table of Take-Home Messages. Questions at the end of each chapter allow readers to test their understanding. Each section also includes references to relevant original literature for further reading. The book offers a valuable resource for students of biology, chemistry and physics with a special interest in biophysics.
List of contents
Chapter 1. Introduction.- Chapter 2. Basics Theory.- Chapter 3. Basics: Methods.- Chapter 4. Application of the Voltage-Clamp Technique.- Chapter 5. Ion-selective Channels.- Chapter 6. Theory of Excitability.- Chapter 7. Carrier-mediated Transport.- Chapter 8. Examples of Application of the Voltage-Clamp Technique.- Chapter 9. Appendix.
About the author
Dr. phil.nat. Jürgen RETTINGER Freelance Electrophysiology Consultant 72070 Tübingen, Germany
Jürgen Rettinger received his doctor degree in physics at Goethe-University in Frankfurt. in 1995. His focus as group leader at Max-Planck-Institute of Biophysics in Frankfurt was research of structure-function relationships of ligand-gated ion channels and teaching electrophysiology at Goethe-University Frankfurt, Shanghai Institutes of Biological Sciences and Fudan-University Shanghai. Between 2008 and 2021 Jürgen Rettinger worked with Multi Channel Systems responsible as product manager for automated electrophysiology.
Silvia SCHWARZ Research Scientist Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function
Fudan University
Shanghai 200433, China
Silvia Schwarz finished her university education in biology and chemistry at Albert-Ludwigs-University Freiburg in 1974. Thereafter, she was educated and worked as teacher in biology and chemistry until 2008. Since then she works as research associate at Shanghai Research Center for Acupuncture and Meridians (Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan Univ.). Silvia Schwarz's main research focus is on antiviral effects of Chinese herbal drugs applying electrophysiological methods.
Prof. Dr. rer.nat. Wolfgang SCHWARZ
Professor for Physics
Institut für Biophysik, Goethe-Universität Frankfurt
Max-von-Laue-Str. 1,
60438 Frankfurt a.M., Germany
Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function
Fudan University
Shanghai 200433, China
Wolfgang Schwarz received his doctor degree in physics at University of Saarland in 1975. Thereafter, he spent two years as postdoc at University of Washington Seattle working on characteristics of ion channels. In 1981 he habilitated in physiology atUniversity of Saarland and received a position as head of a Cell Physiology Laboratory at Max-Planck-Institute of Biophysics Frankfurt. Wolfgang Schwarz's main focus turned to structure-function and regulation of carrier transporters and teaching electrophysiology as professor for physics at Goethe-University Frankfurt, Shanghai Institutes of Biological Sciences and Fudan-University Shanghai. Since 2004 Wolfgang Schwarz is head of the Cell Electrophysiology Laboratory of Shanghai Research Center for Acupuncture and Meridian (Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan Univ.) and concurrent professor at Fudan University.
