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While there are some books that include discussions of individual causes of hypercalcemia, there are none that provide basic guidance on the approach, diagnosis and treatment of hypercalcemia, while also offering an in-depth, detailed, state-of-the-art review of the individual causes by world-renowned experts in the field.
Topics discussed include pathophysiology, differing diagnostic strategies for both the pediatric and adult patient, the various forms and causes of hypercalcemia as well as current treatment regimens and algorithms. Selected chapters are enhanced with illustrative cases, thereby complementing theoretical matter with real-world applications to the practice of medicine, and tables and figures allow the reader to solidify concepts in an easily digestible format.
By integrating an evidence- and guideline-based framework along with an up-to-date, research-based summary of each cause, Hypercalcemia is relevantfor expert clinicians and up-and-coming medical students alike.
List of contents
Normal Regulation of Serum Calcium.- Pathophysiology and Clinical Manifestations of Hypercalcemia.- Diagnostic Approach to the Adult Patient with Hypercalcemia.- Diagnostic Approach and Treatment of the Pediatric Patient with Hypercalcemia.- Primary Hyperparathyroidism.- Genetic Causes of Hypercalcemia/Primary Hyperparathyroidism.- Familial Hypocalciuric Hypercalcemia and Disorders of the Calcium Sensing Receptor.- Overview of Hypercalcemia of Malignancy.- Humoral Hypercalcemia of Malignancy/PTHRP.- Hypercalcemia Related to Osteolytic Metastases and Myeloma.- Hypercalcemia Due to Malignancy Related Production of 1,25 (OH)2.- Vitamin D Intoxication.- Benign 1,25(OH)2 Vitamin D-Mediated Hypercalcemia.- Medication-Induced Hypercalcemia.- Non-Parathyroid Hormone Mediated Endocrine Causes of Hypercalcemia.- Rare and Other Causes of Hypercalcemia.
About the author
Marcella Donovan Walker, MD, New York-Presbyterian Hospital, Columbia University Irving Medical Center, Division of Endocrinology, New York, NY, USA
