Methods In Cell Biology - Intermediate Filament Cytoskeleton

Klappentext Intermediate filaments are a large family of proteins that are the cytoskeletal elements involved in a number of skin, liver, neuromuscular, cardiac, eye and hair diseases. Intermediate filament genes are regulated in a tissue-and cell type-specific manner and their polymerized protein products protects the cells and tissue they are part of against a variety of mechanical and nonmechanical stresses. This book provides a comprehensive resource of methodology essentials, describing a variety of essential tools and assays for studying intermediate filaments. The book provides user-friendly advice and protocols covering all aspects of intermediate filaments including protein isolation and structure, protein and gene regulation, relationship to disease and apoptosis, and associated proteins. Both mammalian and non-mammalian systems and animal models are covered, making this book a must-have for any investigator wishing to study IF genes or their protein products. Zusammenfassung Intermediate filaments are a large family of proteins that are the cytoskeletal elements involved in a number of skin! liver! neuromuscular! cardiac! eye and hair diseases. This book presents a comprehensive resource of methodology essentials! describing a variety of essential tools and assays for studying intermediate filaments.

Product details

• Authors: Pierre A. Coulombe, M. Bishar Omary, M. Bishr Omary, M. Bishr (EDT)/ Coulombe Omary
• Publisher: Academic Press London
• Languages: English
• Product format: Hardback
• Released: 02.12.2004
• EAN: 9780125641739
• ISBN: 978-0-12-564173-9
• No. of pages: 886
• Dimensions: 197 mm x 235 mm x 38 mm
• Series: Methods in Cell Biology; Methods in Cell Biology
• Subjects: Natural sciences, medicine, IT, technology > Biology > Biochemistry, biophysics; SCIENCE / Life Sciences / Biochemistry, biochemistry, proteins