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This important volume offers an integrated view of the principal aspects of immune response to all types of infectious agents, with an emphasis on the immune system as a host defense system. The various infectious agents and diseases are integrated under general topics rather than treated in separate chapters. The book illustrates how the dialogue between different types of pathogens and the host immune system, as well as the cross talk between the different members of the immune response, works. Immunology of Infectious Diseases is valuable reading for microbiologists interested in pathogenesis and immunology; clinicians with an interest in immunology, virology, vaccine development, infectious diseases, bacteriology, parasitology, pathology, and cell biology; and immunologists wanting to expand their knowledge of infectious diseases and their causative agents.
List of contents
Table of Contents
Introduction, Stefan H. E. Kaufmann, Alan Sher, and Rafi Ahmed
I. The Pathogens
1. Overview of the Bacterial Pathogens, Michael Kuhn, Werner Goebel, Dana J. Philpott, and Philippe J. Sansonetti
2. Overview of the Fungal Pathogens, Luigina Romani
3. Overview of the Parasitic Pathogens, Edward J. Pearce and Rick L. Tarleton
4. Overview of the Viral Pathogens, Jonathan W. Yewdell and Jack R. Bennink
II. The Anti-Infective Immune Response
5. Evolution of the Host Defense System, Austin L. Hughes
III. Innate Immunity
6. Phagocytes and Anti-Infective Immunity, Gordon D. Brown and Siamon Gordon
7. Innate Immunity and Bacterial Infections, Emil Unanue
8. Defensins and Cathelicidins—Antimicrobial Peptide Effectors of Mammalian
Innate Immunity, Tomas Ganz and Robert I. Lehrer
9. Innate Immunity to Parasitic Infections, Christopher A. Hunter and Alan Sher
10. Innate Immunity and Fungal Infections, Amy C. Herring and Gary B. Huffnagle
11. Innate Immunity and Viral Infections, Christine A. Biron, Marc Dalod, and Thais P. Salazar-Mather
IV. Acquired Immunity
12. The Th1/Th2 Paradigm in Infections, Tim R. Mosmann and Deborah J. Fowell
13. Immunological Memory and Infection, Rafi Ahmed, J. Gibson Lanier, and Eric Pamer
14. Regional Immune Response to Microbial Pathogens, Marian R. Neutra and Jean-Pierre Kraehenbuhl
15. Acquired Immunity against Bacteria, Helen L. Collins and Stefan H. E. Kaufmann
16. Acquired Immunity against Fungi, Arturo Casadevall
17. Adaptive Immune Effector Mechanisms against Intracellular Protozoa and Gut-
Dwelling Nematodes, Phillip Scott and Richard K. Grencis
18. Acquired Immunity against Viral Infections, Eva Szomolanyi-Tsuda, Michael S. Brehm, and Raymond M. Welsh
V. Pathology
19. Autoimmunity as a Consequence of Infection, Kai W. Wucherpfennig and Nilufer P. Seth
20. Pathology and Pathogenesis of Bacterial Infections, Steffen Stenger and Robert Modlin
21. Pathology and Pathogenesis of Parasitic Disease, Thomas A. Wynn and Dominic Kwiatkowski
22. Pathology and Pathogenesis of Virus Infections, Shawn P. O'Neil, Wun-Ju Shieh, and Sherif R. Zaki
VI. Evasion and Latency
23. Bacterial Persistence: Strategies for Survival
Ernesto J. Muñoz-Elías and John D. McKinney
24. Viral Immune Evasion
David C. Johnson and Grant McFadden
25. Immune Evasion by Parasites
John M. Mansfield and Martin Olivier
VII. Immunogenetics
26. Immunogenetics of the Host Response to Bacteria and Parasites in
Humans, Laurent Abel and Jean-Laurent Casanova
27. Immunogenetics of the Host Response to Bacteria in Mice, Philippe Gros and Erwin Schurr
28. Immunogenetics of the Host Response to Viral Infections, Michel Brahic, Charles M. Bangham, Gabriel Gachelin, and Jean-François Bureau
VIII. Immune Intervention
29. Immune Intervention in Tuberculosis, Douglas B. Young and Brian D. Robertson
30. Immune Intervention in AIDS, Guido Silvestri and Mark B. Feinberg
Summary
Offering an integrated view of principal aspects of immune response to all types of infectious agents, this title deals with the immune system primarily as a host defense system. Various infectious agents and diseases are integrated under general topics rather than treated in separate chapters.
