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Neurotransmitter sind ein wesentlicher Bestandteil des zentralen Nervensystems, das Nervenimpulse zwischen Rezeptoren und Effektoren koordiniert. "Neurotransmitters, Drugs and Brain Function" stellt eine Verbindung her zwischen grundlegenden Aspekten der Aktivität von Neurotransmittern auf Rezeptor- und Synapsenebene und ihrer jeweiligen Funktion bei normaler Hirnfunktion, bei Erkrankungen und bei Drogeneinwirkung. Dieser Band untersucht, wie die zentrale synaptische Wirkung bestimmter Drogen auf die mögliche Beteiligung von Neurotransmittern bei der Entstehung von Krankheiten schließen lässt und wie die Wirkungsweise von Medikamenten bei solchen Erkrankungen erklärt werden kann.
"Neurotransmitters, Drugs and Brain Function" ist für Studenten und Forscher in den Bereichen Pharmakologie, Neurowissenschaft, Medizin und Psychologie von unschätzbarem Wert.
List of contents
List of Contributors.
Preface.
SECTION A: BASIC ASPECTS OF NEUROTRANSMITTER FUNCTION.
Neurotransmitter Systems and Function: Overview (R.A. Webster).
Control of Neuronal Activity (D.A. Brown) .
Neurotransmitter Receptors (A.J. Gibb).
Neurotransmitter Release (S.C. Stanford).
SECTION B: NEUROTRANSMITTERS AND SYNAPTIC TRAANSMISSION.
Basic Pharmacology and Drug Effects on Neurotransmitter Function (R.A. Webster).
Acetylcholine (R.A. Webster).
Dopamine (R.A. Webster).
Noradrenaline (S.C. Stanford).
5-Hydroxytryptamine (S.C. Stanford).
Amino Acids: Excitatory (A.H. Dickenson).
Amino Acids: Inhibitory (M. Farrant).
Peptides (A.H. Dickenson).
Other Transmitters and Mediators (R.A. Webster).
SECTION C: NEUROTRANSMITTERS IN DRUG ACTION AND DISEASE STATES.
Study and Manipulation of Neurotransmitter Function in Humans (R.A. Webster).
Disease of the Basal Ganglia (R.A. Webster).
The epilepsies (R.A. Webster).
Schizophrenia (R.A. Webster)
Alzheimer's Disease (R.A. Webster).
Anxiety (S.C. Stanford).
Depression (S.C. Stanford).
Pain and Analgesia (A.H. Dickenson).
SECTION D: NEUROTRANSMITTERS AND BEHAVIOUR.
Sleep and Waking (R.A. Webster and S.C. Stanford)
Drug Dependence and Abuse (A.H. Dickenson).
Index.
About the author
Roy Webster is the editor of
Neurotransmitters, Drugs and Brain Function, published by Wiley.
Summary
This text looks at the basic aspects of the activity of neurotransmitters at the receptor and synaptic level with their role in normal brain function, disease states and drug action.
Additional text
"the editor of this textbook is to be congratulated" (Human Psychpharmacology, April 2002)
Report
"the editor of this textbook is to be congratulated" (Human Psychpharmacology, April 2002)
"...describes what neurotransmitters do, how they do it, and how their activity is involved in brain functions, as well as how it's affected by drugs and disease." (SciTech Book News, Vol. 26, No. 2, June 2002)
"...the first half of the book on basic aspects of neurotransmission is a delight and is a must for medicinal chemists..." (Jnl of Medicinal Chemistry, Vol.45, No.15, 2002)
"...a valuable addition to any post-graduate psychiatric library..." (Int Jnl of Geriatric Psychiatry, No. 17, 2002)
"...this is an outstanding book...we should all eagerly adopt this text as an excellent reference book that ought not to be missing from our shelves..." (Journal of Chemical Neuroanatomy, Vol 31 (1), 2006)
