Cannabis Use, Neurobiology, Psychology, and Treatment

Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol, many of which are neuroactive.

List of contents

Preface
I. Setting the scene and introductory chapters
1. Metabolomics of the cannabis plant
Mickel Hiebert-Giesbrecht, Claudia Torres-Calzada and David Scott Wishart
2. The roots of Cannabis sativa: chemical and pharmacological profile
L A. Rolim
3. Cannabis related compounds in beverages and food
Ilaria Di Marco Pisciottano
4. The impact of prenatal cannabis exposure: an overview
Natalia Kleinhans
5. Cannabis Genotoxicity and Cancer Incidence: Highly Concordant Synthesis of European and USA Datasets
Albert Stuart Reece and Gary K. Hulse
6. Cannabis Genotoxicity and Cancer Incidence: A Highly Concordant Synthesis of European and USA Datasets
Albert Stuart Reece and Gary K. Hulse
7. Cannabis, Cognitive impairment and Car Crash risk
U.W. Preuss
II. Cannabis usage
8. Recreational cannabis use: a French perspective of adverse effects
Emilie Bouquet, Emilie Jouanjus and Maryse Lapeyre-Mestre
9. Acute and chronic impact of cannabis on human cognition
Justin Matheson and Bernard Le Foll
10. Polydrug users, use of cannabidiol (CBD) and abuse potential/Polydrug users, use of cannabinoids and abuse potential
Kerri Alexandra Schoedel
11. Cannabis stigmas: a narrative of features
Matt Reid
12. Alterations of THC and CBD ratios and impact on cognition
Erica Zamberletti
13. When cannabis is used for medicinal purposes: a focus on back pain
R. L. Price III
III. Pharmacological and Physiological Aspects
14. Cannabis, cannabinoids and receptor responses
Yi Yang, Roya Derwish and Lakshmi P. Kotra
15. Cannabidiol (CBD): abuse potential and withdrawal
Kenneth W. Sommerville and Beatrice Setnik
16. 4,5- Dihydro-1H-pyrazole/3,4-Diarylpyrazoline class of cannabinoid-1 (CB1R) receptor antagonists and their potential in medicinal applications
Malliga R. Iyer
IV. Neurobiology of cannabis
17. Neurobiology of cannabis
Rohit Goyal and Deepak Kumar
18. The kynurenine pathway, neurobiology and cannabis misuse: a new narrative
Nuria Morales-Puerto and Esther O'Shea
19. Central nervous system cancers and use of cannabis and related products: an updated narrative
J. Eduardo Rodriguez Almaraz and Nicholas Butowski
20. Chronic cannabis users: links with glutamate and resting state connectivity
S.D. Newman
21. Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRI
Thorsten Rudroff
22. Genetic Variation and Acute Responses to Cannabis
Bernard Le Foll, Zoe Bourgault and Justin Matheson
23. Cell Signaling of the CB1 Cannabinoid Receptor via beta-arrestins, Cannabinoid Receptor Interacting Protein (CRIP1a) and other regulatory proteins
Allyn C. Howlett
24. Cannabis and impact on memory: from in utero to adults
Jennifer Willford, Meaghan Hazelet, Mohamad Khalaifa, Natacha DeGenna and Gale A. Richardson
25. Central CB1 receptors and age-related changes: investigating the effects of DELTA-9-tetrahydrocannabinol
Brett C. Ginsburg and Hanana AlTfaili
26. Alcohol, cannabis and visual memory
Concepcion Vinader-Caerols
V. Neurobiology of cannabinoids
27. The role of Delta-FosB in the plasticity of the cannabinoid system
Arturo Venebra-Munoz and Sara Mejía-Chávez
28. Functional profile of synthetic cannabinoid receptor agonists: exploring cannabinoid and non-cannabinoid targets
Shivani Sachdev, Marina Santiago and Chris Bladen
29. Linking the G protein-coupled orphan receptor GPR55 to the cannabinoid receptors (CB1 and CB2): a new narrative
Paula Morales, Raquel Guerrero-Alba and B.A. Marichal-Cancino
30. Proteomic analysis of cannabinoids in human oligodendrocytes
Valéria Almeida
31. Cannabinoids and endocannabinoid signaling at the basal forebrain cholinergic system
Rafael Rodriguez
32. Cannabidiol (The major non-psychotropic cannabinoid in the cannabis plant) and the PI3K/Akt pathway in the CNS
Nadja Schroder
33. Effects of cannabidiol and other phytocannabinoids on ion channels
Murat Oz, Keun-Hang Susan Yang, Mohamed Mahgoub, Georg Petroianu and Dietrich Lorke
34. Cannabis, neurodevelopment and the "two-hit hypothesis"
Elisa Guma, Lani Cupo and Mallar Chakravarty
VI. New and synthetic cannabinoids
35. Impact of tetrahydrocannabinol (THC ) and synthetic "spice"cannabinoids on nicotine use and abuse
Christie Dawn Fowler and Angeline Dukes
36. Synthetic cannabinoids: how do they compare to DELTA9-tetrahydrocannabinol: neurological effects and beyond
Chris S. Breivogel
VII. Biomarkers, analysis and screening
37. The DSM-5 criteria of cannabis use disorder: methods and applications
Mahadev Sen, Siddharth Sarkar and Yesh Singh
38. Cannabis and clinical high risk for psychosis: monitoring and smartphones
Jean Addington
VIII. Impact on non-neurological systems
39. The impact of cannabis and cannabinoids on the skin
Jane M. Grant-Kels
40. Cannabis consumption in reproduction and teratogenicity
Susana Sa and B.M. Fonseca
41. Cannabis compounds and putative cytotoxicity: profile of cancer cells
Hadar Peeri and Hinanit Koltai
IX. Treatments, strategies and resources
42. Motivational Interviewing for Cannabis Use Disorders: a narrative review from research to practice
Hugo López-Pelayo, Maria Teresa Pons-Cabrera, Clara Oliveras Salvà and Pablo Rodrigo Guzmán Cortez
43. An Overview of Current Pharmacologic Interventions for Management of Cannabis Withdrawal and the Evidence for Their Use
David Wolinsky
44. Managing cannabinoid hyperemesis syndrome in paediatrics: A new narrative review
Justin P. Reinert
45. Gabapentinoids for the Treatment of Cannabis Use Disorder: A Focus on Human Laboratory Research
Joshua A. Lile
46. Treating psychosis in users of synthetic cannabinoids
T. Klimenko and Svetlana Shakhova
X. Resources
47. Cannabis and Web based Resources
Rajkumar Rajendram

About the author

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.Dr. Patel is a Reader at the University of Westminster. After completing his PhD at King’s College London, he continued his research experience by undertaking his post-doctoral studies in the laboratory of Professor Cunningham in the Department of Biochemistry at the Wake Forest University School of Medicine, (Winston-Salem, NC, USA). This extensive project involved investigating mechanisms of hepatic mitochondrial ribosome dysfunction in alcoholic liver disease (ALD) using biophysical and proteomic techniques. These studies have led to new avenues in determining the pathology of ALD. His teaching areas at both post-graduate and undergraduate levels include clinical biochemistry, investigative pathology and laboratory investigation.Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

Product details

• Authors: Colin R. (Professor of Clinical Psychobiol Martin, Colin R Martin, Colin (Professor of Clinical Psychobiolo R Martin
• Assisted by: Vinood B. Patel (Editor), Vinood B. B. Patel (Editor), Colin R Martin (Editor), Colin R. Martin (Editor), Colin R. Martin (Editor), Colin R. N. Martin (Editor), Vinood B Patel (Editor), Vinood B. Patel (Editor), Vinood B. (Reader Patel (Editor), Patel Vinood B. (Editor), Victor R Preedy (Editor), Victor R. Preedy (Editor), Colin R Martin (Editor), Colin (Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing University of Suffolk R Martin (Editor), Colin (Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing; University of Suffolk R Martin (Editor), Colin (Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and WellbeingUniversity of Suffolk R Martin (Editor), Colin R. Martin (Editor), Victor R Preedy (Editor)
• Publisher: ELSEVIER SCIENCE BV
• Languages: English
• Product format: Hardback
• Released: 01.06.2023
• EAN: 9780323898621
• ISBN: 978-0-323-89862-1
• No. of pages: 670
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; SCIENCE / Life Sciences / Neuroscience, MEDICAL / Neurology, Neurology & clinical neurophysiology, Neurosciences, Neurology and clinical neurophysiology