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Informationen zum Autor Malcolm Whitman, Amy Sater Klappentext Focusing on specific pathways or pathway components! Analysis of Growth Factor Signaling in Embryos provides the methods and guidelines for experimental design to study cell signaling in vertebrate embryos. With contributions from top researchers! the book incorporates molecular! cellular! and systems analysis while discussing signal transduction! protein phosphorylation! embryogenesis! pattern formation! and morphogenesis. It also covers multiple types of signaling components! including receptors! GTPases! and effector kinases! and discusses all of the major vertebrate embryonic model systems! such as Xenopus! mouse! zebrafish! and chick. This book will provide a foundation for further explorations of the cellular regulatory mechanisms governing vertebrate embryonic development. Zusammenfassung Focusing on specific pathways or pathway components, this book provides the methods and guidelines for experimental design to study major aspects of cell signaling in vertebrate embryos. It covers a broad range of topics in signaling and a variety of current model organisms. Inhaltsverzeichnis SIGNALS AND PATHWAYS Analysis of Canonical Wnt Signaling in Xenopus Embryos Wilson K. Clements and David Kimelman How to Assay Non-Canonical Wnt Signaling: A Critical Analysis Michael Kühl and Randall T. Moon Regulation of TGF-ß Family Activity by Proprotein Processing Shailaja Sopory and Jan L. Christian Analysis of MAP Kinase Pathways in Vertebrate Development Amy K. Sater and Heithem M. El-Hodiri Analysis of Retinoid Signalling in Embryos Malcolm Maden Wnt Signaling via the Rho Family of GTPases during Embryonic Development Raymond Habas and Xi He Phosphospecific Antibodies as Tools for the Study of Signal Transduction during Development Malcolm Whitman IONIC SIGNALS Dynamic Analysis of Calcium Signaling in Animal Development Diane C. Slusarski Strategies and Techniques for Investigation of Biophysical Signals in Patterning D.S. Adams and M. Levin TRANSCRIPTIONAL REGULATION OF TARGET GENES Expression Profiling in Xenopus Embryos Curtis Altmann Chromatin Immunoprecipitation for in vivo Studies of Transcriptional Regulation during Development Daniel R. Buchholz! Bindu D. Paul! and Yun-Bo Shi EMERGING STRATEGIES FOR THE ANALYSIS OF SIGNALING IN DEVELOPMENT Chemical Biology in Zebrafish Vascular Development Joanne Chan and Thomas M. Roberts Investigating Gastrulation Karen Symes Bringing Small Molecule Regulation of Protein Activity to Developmental Systems Karen J. Liu! Jason E. Gestwicki! and Gerald R. Crabtree Systems Analysis of Signaling Pathways Gregory R. Hoffman! Kevin Brown! Adrian Salic! and Ethan Lee INDEX ...
