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Informationen zum Autor Peter Wipf is the Director of the Combinatorial Chemistry Center (CCC) and the Center for Chemical Methodologies and Library Development (UPCMLD) which are involved in many collaborative projects in Chemical Biology. He is also a founding member of the Center for Medical Countermeasures Against Radiation (CMCR) and the University of Pittsburgh Center for Chemical Diversity (UPCDC). He has served on the organizing committee of several conferences and workshops, including the NSF Workshop on Organic Synthesis. He is a member of several editorial boards, including Medicinal Chemistry Letters (ACS MCL), Organic Reactions (OR), and Organic Syntheses (OS). Klappentext Organic syntheses consists of protocols for the synthesis of useful chemical compounds. "Organic Syntheses! Volume 87" provides carefully checked and edited experimental protocols that describe important synthetic methods! transformations! reagents! and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. For each protocol! safety warnings are presented along with detailed experimental descriptions for the preparation! purification! and identification of the compound. Additionally! special reaction conditions are also detailed. This current volume continues the tradition of providing significant and interesting procedures for synthetic chemists working in increasingly diverse areas. Zusammenfassung Organic syntheses consists of protocols for the synthesis of useful chemical compounds. Organic Syntheses! Volume 87 provides carefully checked and edited experimental protocols that describe important synthetic methods! transformations! reagents! and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. Inhaltsverzeichnis Metal-Free One-Pot Oxidative Amination of Aromatic Aldehydes: Conversion of Benzaldehyde to N-Benzoyl Pyrrolidine 1 Kekeli Ekoue-Kovi and Christian Wolf A Practical and Scalable Synthesis of N-Halo Compounds: 2-Chloro-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline 8 Yong-Li Zhong and Paul G. Bulger Regioselective C-4 Bromination of Oxazoles: 4-Bromo-5-(Thiophen-2-YL) Oxazole 16 Bryan Li, Richard A. Buzon, and Zhijun Zhang Synthesis of Spiroborate Esters from 1,2-Aminoalcohols, Ethylene Glycol and Triisopropyl Borate: Preparation of (S)-1-(1,3,2-Dioxaborolan-2-Yloxy)-3-Methyl-1,1-Diphenylbutan-2-Amine 26 Viatcheslav Stepanenko, Kun Huang and Margarita Ortiz-Marciales Catalytic Enantioselective Borane Reduction of Benzyl Oximes: Preparation of (S)-1-Pyridin-3-YL-Ethylamine BIS Hydrochloride 36 Kun Huang and Margarita Ortiz-Marciales Stereoselective Synthesis of 3-Arylacrylates by Copper-Catalyzed Syn Hydroarylation 53 Naohiro Kirai and Yoshihiko Yamamoto Preparation of (S)-3,3'-BIS-Morpholinomethyl-5,5',6,6',7,7',8,8'-Octahydro-1,1'-BI-2-Naphthol 59 Mark Turlington and Lin Pu Catalytic Asymmetric Addition of an In-Situ Prepared Arylzinc to Cyclohexanecarboxaldehyde: (R)-(+)-¿-Cyclohexyl-3-Methoxy-Benzenemethanol 68 Albert M. DeBerardinis, Mark Turlington, and Lin Pu Microwave-Assisted Synthesis of 1,3-Dimesitylimidazolinium Chloride 77 Morgan Hans and Lionel Delaude Synthesis of (3-Chlorobutyl)Benzene by the Cobalt-Catalyzed Hydrochlorination of 4-Phenyl-1-Butene 88 Boris Gaspar, Jerome Waser, and Erick M. Carreira Synthesis of Substituted Indazoles via (3+2) Cycloaddition of Benzyne and Diazo Compounds 95 Feng Shi and Richard C. Larock Palladium-Catalyzed Cross-Coupling Using an Air-Stable Trimethylaluminum Source. Preparation of Ethyl 4-Methylbenzoate 104 Andrej Vinogradov and Simon Woodward Synthesis of Dimethyl 2-Phenycyclopropane-1,1-Dicarboxylate Using an Iodo...
