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1,2,3-Triazoles are an important group of heterocyclic compounds that are biologically active pharmacophore such as antimicrobial, antiviral, anti-diabetic, antiulcer and anticancer activity. This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type) etc.Chalcone is an aromatic ketone and an enone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones/ chalconoids. These scaffolds found in many naturally occurring sources and used as lead compounds for the synthesis of numerous heterocyclics which possess diverse biological activities and play pivotal role. Indole chemistry began to develop with the study of the dye indigo. Indigo can be converted to isatin and then to oxindole could converted to indole using zinc dust. These reported as biologically active, with a wide range of therapeutic properties such as antibacterial, antifungal, antiviral, antimalarial, anti-HIV, anticancer etc.
About the author
Dr. Raghavender Matta did M.Sc Organic Chemistry in 2010 followed by Ph.D awarded in 2019 under the guidance of Dr.Jalapathi Pochampally from Osmania University,Hyderabad, Telangana,India. He published about 12 research papers in reputed international journals, presently he is working as Assistant Professor in Chemistry for Jagruthi Degree College.
